Results 111 to 120 of about 66,929 (277)

OPREMA und ZRA 1 - die Rechenmaschinen der Firma Carl Zeiss Jena [PDF]

open access: yes, 2006
Die Entwicklungsarbeiten für die OPREMA (OPtikREchenMAschine) begannen im VEB Carl Zeiss Jena 1954 und wurden bereits 1955, d.h. nach 7 1/2 Monaten (!), abgeschlossen.
Kerner, Immo O.
core  

Unraveling in vitro phase separation and aggregation properties of the structured region of FMRP and the impact of Fragile X syndrome‐linked mutations

open access: yesThe FEBS Journal, EarlyView.
Fragile X messenger ribonucleoprotein 1 (FMRP) is a multidomain RNA‐binding protein associated with Fragile X Syndrome (FXS). We found that its N‐terminal structured region has an intrinsic propensity to undergo liquid–liquid phase separation and fibril formation. FXS‐associated mutations perturb protein stability and aggregation propensity, suggesting
Flavia Catalano   +10 more
wiley   +1 more source

Clonal Hematopoiesis and CAR T Cell Therapy: From Biological Crosstalk to Clinical Implications

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Clonal hematopoiesis (CH) is increasingly recognized as a significant biological phenomenon in aging and cancer, marked by the expansion of hematopoietic stem and progenitor cells harboring somatic mutations in genes associated with myeloid neoplasms.
Wei Du   +4 more
wiley   +1 more source

Über die drucklose Hydrierung von 3-Cyanpyridin

open access: yesCHIMIA, 1969
Eberhard Fischer   +2 more
doaj   +1 more source

Über ein „Prinzip der strikten simultanen Rekursion“ beim Entwurf von Rechnerarchitekturen und -arithmetiken [PDF]

open access: yes, 2008
Über eine Mitte 1988 begonnene Studienarbeit zum Entwurf digitaler Verarbeitungsprinzipien der Numerik am Institut für Informatik und Rechentechnik der ADW, über ihre Orientierung und Ergebnisse, den thematischen Bruch durch die Wende und den Abbruch bei
Brosch, Hans-Jürgen
core  

Mechanisms of Therapeutic Resistance and Recent Advances in Glioblastoma Treatment

open access: yesImmunology &Cell Biology, EarlyView.
Three interconnected processes in glioblastoma (GBM) biology: initiation, stratification, and immunosuppression. 1) Initiation: GBM initiation is proposed to occur through migration of TERT mutation‐bearing neural stem cells from the subventricular zone to the frontal and temporal cortices, where a subsequent oncogenic transformation drives their ...
Emerson Achari   +6 more
wiley   +1 more source

Forschung zur Leistungsmodellierung von Rechnerinstallationen in Rechenzentren der DDR [PDF]

open access: yes, 2008
In diesem Beitrag werden einige ausgewählte Ergebnisse auf dem Gebiet der Forschung zur Leistungsmodellierung von Rechnerinstallationen dargestellt, die der Autor und seine Mitarbeiter in den 70er und 80er Jahren erzielt haben.
Bergholz, Gerhard
core  

R‐Loops Mediated Odontogenic Differentiation of hDPSCs by Activating the cGAS‐STING Pathway Under Inflammatory Microenvironment

open access: yesOral Diseases, EarlyView.
ABSTRACT Background R‐Loops are three‐stranded DNA/RNA hybrids implicated in immune responses. Their role in mesenchymal stem cell differentiation, particularly in dental pulp regeneration under inflammation, remains unclear. Methods Rat pulpo‐dentinal complex (PDC) injury models and LPS‐stimulated human dental pulp stem cells (hDPSCs) were used.
Yun Yang   +5 more
wiley   +1 more source

Advancing Computational Thinking in Mathematics Education: a Systematic Review of Indonesian Research Landscape

open access: yesJTAM (Jurnal Teori dan Aplikasi Matematika)
Computational Thinking (CT) has emerged as a crucial and foundational skill in the 21st century, capturing the attention of researchers across various domains, including mathematics education in Indonesia.
Edi Irawan   +2 more
doaj   +1 more source

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