DDR: efficient computational method to predict drug–target interactions using graph mining and machine learning approaches [PDF]
, 2018 Rawan S. Olayan +2 more
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Derived stacks in symplectic geometry
, 2018 This is a survey paper on derived symplectic geometry, that will appear as a chapter contribution to the book "New Spaces for Mathematics and Physics", edited by Mathieu Anel and Gabriel Catren.
Calaque, Damien
core +3 more sources
Active Learning for the Discovery of Antiviral Polymers
Macromolecular Rapid Communications, EarlyView.Machine learning and active learning are integrated to accelerate the discovery of antiviral polymers. Molecular descriptors derived from polymer composition enable predictive modeling of antiviral activity, while unsupervised clustering explores chemical diversity. The active learning workflow identifies optimal candidates for synthesis, demonstrating
Clodagh M Boland +2 more
wiley +1 more source
Results and Exploratory Biomarker Analyses of a Phase II Study CHANGEABLE: Combination of PD-1 Inhibitor and Niraparib in GErm-Line-mutAted Metastatic Breast Cancer. [PDF]
MedComm (2020)This phase II trial evaluated the efficacy and safety of niraparib combined with HX008 in metastatic breast cancer (MBC) patients with germline DNA damage response (DDR) gene mutations. This chemotherapy‐free regimen demonstrates promising efficacy and a tolerable safety profile in MBC patients with germline DDR mutations, providing a novel therapeutic
Zhang J +9 more
europepmc +2 more sources
Terrell‐Penrose‐Effekt erstmals im Labor demonstriert: Ein Augenblick bei Lichtgeschwindigkeit
Physik in unserer Zeit, EarlyView.Der Terrell‐Penrose‐Effekt beschreibt, wie ein Objekt erscheint, das sich gegenüber einem Beobachter relativistisch schnell bewegt. Ist die Lorentz‐Kontraktion sichtbar? Wegen der Zeitverzögerung der unterschiedlich langen Lichtwege von der Oberfläche des Objekts sollte es auf besondere Weise verformt erscheinen.
Philipp Haslinger +3 more
wiley +1 more source
Large-Signal Simulation of 94 GHz Pulsed Silicon DDR IMPATTs Including the Temperature Transient Effect [PDF]
, 2012 In this paper large-signal modeling and simulation has been carried to study the frequency chirping due to temperature transients and the large-signal power and efficiency of pulsed silicon Double-Drift Region (DDR) Impact Avalanche Transit Time (IMPATT)
Acharyya, A. +2 more
core +1 more source
Structural Concrete, EarlyView.Abstract After a blossoming pre‐World War II (WWII) period, the concrete construction industry in then‐socialist Hungary existed in a relative isolation from the Western World during the mid‐20th century. In this paper, we focus on the body of work of one of the then newly established state‐owned design offices, IPARTERV, to show how the isolation ...
Orsolya Gáspár, Péter Haba
wiley +1 more source
Staging concept for aging management: Definition, mechanism, and coping strategies
VIEW, EarlyView.We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
Design and Implementation of a High Efficient DDR SDRAM Controller Applied in TOF-MS [PDF]
, 2015 Qian Li, Ming Wang, Yang Yu
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