Results 71 to 80 of about 66,929 (277)
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum +5 more
wiley +1 more source
Berichte zur Wissenschaftsgeschichte, EarlyView.Since late 2021, serious allegations have been made against physicist Erwin Schrödinger, ranging from pedophilia to serial sexual abuse. These accusations have significantly tarnished the Nobel Prize winner's public reputation. The ongoing debate has repeatedly raised the question of whether, and to what extent, these grave allegations are justified ...
Magdalena Gronau, Martin Gronau
wiley +1 more source
Las Farianas: Reintegration of former female FARC fighters as a driver for peace in Colombia
Cuadernos de Economía, 2019 The 2016 peace agreement includes comprehensive prescriptions for the so-called “reincorporation” of former combatants into the social, economic and political life of Colombia.
Laura Camila Barrios Sabogal +1 more
doaj +1 more source
Informatik in der DDR - eine Bilanz [PDF]
, 2006 Tagungsband zu den Symposien "Informatik in der DDR" 7. bis 9. Oktober 2004 in Chemnitz und 11. bis 12.
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iNew Medicine, EarlyView.ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu +5 more
wiley +1 more source
IET Cyber-Physical Systems, 2019 This study proposes a novel user-centric cyber-physical framework to achieve distributed demand response (DDR) in a distribution system where local schedulers (LS) present at individual buses program both local and non-local loads to reduce the maximum ...
Swaroop Ranjan Mishra +3 more
doaj +1 more source
Planen fuer das Kollektiv Handlungs- und Gestaltungsspielraeume von Architekten und Stadtplanern in der DDR; Dokumentation des 4. Werkstattgespraechs vom 15.-16. Oktober 1998 [PDF]
, 1999 'Die hier dokumentierten Beitraege des 4. Werkstattgespraechs zur Bau- und Planungsgeschichte der DDR widmen sich dem Thema der Handlungs- und Gestaltungsspielraeume von Stadtplanern und Architekten in der DDR.
Barth, Holger (ed.) +1 more
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Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress
Interdisciplinary Medicine, EarlyView.This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu +13 more
wiley +1 more source
Technologietransfer am Beispiel von DABA 1600 [PDF]
, 2008 DABA 1600 war die DDR-Eigenentwicklung eines relationalen Datenbankmanagementsystems (DBMS) für PDP-11-kompatible Systeme wie dem Kleinrechner robotron K1630. Es wurde in den achtziger Jahren in Kooperation vom Zentrum für Forschung und Technik (ZFT) des
Wiggert, Karl-Heinz, Demuth, Birgit
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Deubiquitinase USP38 Stabilizes PLK1 Expression to Boost DNA Damage Repair in Ovarian Cancer
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Ovarian cancer (OC) is one of the most prevalent and severe gynecological malignant tumors. DNA damage repair (DDR) is essential in maintaining genome stability. This study aims to investigate the effects and mechanisms of USP38 and PLK1 on DNA damage repair and malignant behavior in OC cells.
Yuan Ma, Ying Li, Kai‐Li Li
wiley +1 more source