Results 251 to 260 of about 334,258 (285)
Gut metatranscriptomics based de novo assembly reveals microbial signatures predicting immunotherapy outcomes in non-small cell lung cancer. [PDF]
J Transl MedDora D +6 more
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Exploring the Venom Gland Transcriptome of <i>Bothrops asper</i> and <i>Bothrops jararaca</i>: De Novo Assembly and Analysis of Novel Toxic Proteins. [PDF]
Toxins (Basel)Espín-Angulo J, Vela D.
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De novo assembly and annotation of Popillia japonica's genome with initial clues to its potential as an invasive pest. [PDF]
BMC GenomicsCucini C +10 more
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Using SPAdes De Novo Assembler
Current Protocols in Bioinformatics, 2020AbstractSPAdes—St. Petersburg genome Assembler—was originally developed for de novo assembly of genome sequencing data produced for cultivated microbial isolates and for single‐cell genomic DNA sequencing. With time, the functionality of SPAdes was extended to enable assembly of IonTorrent data, as well as hybrid assembly from short and long reads ...
Andrey, Prjibelski +4 more
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Genovo:De NovoAssembly for Metagenomes
Journal of Computational Biology, 2010Next-generation sequencing technologies produce a large number of noisy reads from the DNA in a sample. Metagenomics and population sequencing aim to recover the genomic sequences of the species in the sample, which could be of high diversity. Methods geared towards single sequence reconstruction are not sensitive enough when applied in this setting ...
Jonathan, Laserson +2 more
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2013
In an ideal case, an assembly algorithm should merge overlapped reads to one long continuous sequence, called contig, which is a chromosome in the primitive genome. But due to sequencing errors and the existence of unsequenced parts, contigs gained from the assembly algorithm are not complete enough to form chromosomes.
Ali Masoudi-Nejad +2 more
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In an ideal case, an assembly algorithm should merge overlapped reads to one long continuous sequence, called contig, which is a chromosome in the primitive genome. But due to sequencing errors and the existence of unsequenced parts, contigs gained from the assembly algorithm are not complete enough to form chromosomes.
Ali Masoudi-Nejad +2 more
openaire +1 more source
Practical evaluation of 11 de novo assemblers in metagenome assembly
Journal of Microbiological Methods, 2018Next Generation Sequencing (NGS) technologies are revolutionizing the field of biology and metagenomic-based research. Since the volume of metagenomic data is typically very large, De novo metagenomic assembly can be effectively used to reduce the total amount of data and enhance quality of downstream analysis, such as annotation and binning. Although,
Esmaeil Forouzan +4 more
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2011
An imperative first step in the characterization of a species or individual is the sequencing and subsequent assembly and analysis of its genome. High-throughput sequencing technology has ushered in a new way of thinking about this fundamental undertaking. Next-generation sequencing machines produce reads through highly parallel operation and produce a
Douglas W. Bryant, Todd C. Mockler
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An imperative first step in the characterization of a species or individual is the sequencing and subsequent assembly and analysis of its genome. High-throughput sequencing technology has ushered in a new way of thinking about this fundamental undertaking. Next-generation sequencing machines produce reads through highly parallel operation and produce a
Douglas W. Bryant, Todd C. Mockler
openaire +1 more source
De Novo Transcriptome Assembly in Polyploid Species
2017In the absence of a reference genome, the ultimate goal of a de novo transcriptome assembly is to accurately and comprehensively reconstruct the set of messenger RNA transcripts represented in the sample. Non-reference assembly of the transcriptome of polyploid species poses a particular challenge because of the presence of homeologs that are difficult
Juan J, Gutierrez-Gonzalez +1 more
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