Results 231 to 240 of about 111,403 (262)
A de novo genome assembly of Solanum bulbocastanum Dun., a Mexican diploid species reproductively isolated from the A-genome species, including cultivated potatoes. [PDF]
G3 (Bethesda)Hosaka AJ, Sanetomo R, Hosaka K.
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De Novo Genome Assembly for an Endangered Lemur Using Portable Nanopore Sequencing in Rural Madagascar. [PDF]
Ecol EvolHauff L +6 more
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De novo assembly and phasing of a Korean human genome
Nature, 2016 Advances in genome assembly and phasing provide an opportunity to investigate the diploid architecture of the human genome and reveal the full range of structural variation across population groups. Here we report the de novo assembly and haplotype phasing of the Korean individual AK1 (ref. 1) using single-molecule real-time sequencing, next-generation
Alex Hastie +2 more
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Genetic variation and the de novo assembly of human genomes [PDF]
Nature Reviews Genetics, 2015 The discovery of genetic variation and the assembly of genome sequences are both inextricably linked to advances in DNA-sequencing technology. Short-read massively parallel sequencing has revolutionized our ability to discover genetic variation but is insufficient to generate high-quality genome assemblies or resolve most structural variation.
Mark Chaisson +2 more
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De novo assembly of a Chinese soybean genome
Science China Life Sciences, 2018Soybean was domesticated in China and has become one of the most important oilseed crops. Due to bottlenecks in their introduction and dissemination, soybeans from different geographic areas exhibit extensive genetic diversity. Asia is the largest soybean market; therefore, a high-quality soybean reference genome from this area is critical for soybean ...
Yanting, Shen +9 more
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MELC Genomics: A Framework for De Novo Genome Assembly
Journal of Computational Biology, 2018The development of next-generation sequencing platforms increased substantially the capacity of data generation. In addition, in the past years, the costs for whole genome sequencing have been reduced that made it easier to access this technology.
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Whole-Genome Sequencing for Comparative Genomics and De Novo Genome Assembly
2015Next-generation sequencing technologies for whole-genome sequencing of mycobacteria are rapidly becoming an attractive alternative to more traditional sequencing methods. In particular this technology is proving useful for genome-wide identification of mutations in mycobacteria (comparative genomics) as well as for de novo assembly of whole genomes ...
Benjak A, Sala C, Hartkoorn RC
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Towards accurate de novo assembly for genomes with repeats
2017 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), 2017De novo genome assemblers designed for short k-mer length or using short raw reads are unlikely to recover complex features of the underlying genome, such as repeats hundreds of bases long. We implement a stochastic machine-learning method which obtains accurate assemblies with repeats and self-validates assemblies via consensus.
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Evaluation of nine popular de novo assemblers in microbial genome assembly
Journal of Microbiological Methods, 2017Next generation sequencing (NGS) technologies are revolutionizing biology, with Illumina being the most popular NGS platform. Short read assembly is a critical part of most genome studies using NGS. Hence, in this study, the performance of nine well-known assemblers was evaluated in the assembly of seven different microbial genomes. Effect of different
Esmaeil, Forouzan +3 more
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