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Algorithms for de novo assembly of large genomes
2019Tehnologije za sekvenciranje genoma nisu u mogućnosti interpretirati DNA molekule u cijelosti te je to dovelo do razvoja računalnih metoda koje spajaju kratke fragmente u procesu koji podsjeća na rješavanje slagalica. Alati namijenjeni za ovaj problem nazivaju se asembleri čiji je dizajn baziran na pretpostavci da slični fragmenti potječu iz iste ...
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De novo chromosome level assembly of a plant genome from long read sequence data
Plant Journal, 2022Bruce Topp +2 more
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Haplotype-resolved de novo assembly using phased assembly graphs with hifiasm
Nature Methods, 2021Gregory Concepción +2 more
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Sequencing and de Novo Assembly of Abaca (Musa textilis Née) var. Abuab Genome
Genes, 2021Dapeng Zhang +2 more
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Reference-Guided De Novo Genome Assembly of the Flour Beetle Tribolium freemani
International Journal of Molecular Sciences, 2022Brankica Mravinac +2 more
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De novo sequencing and assembly of complex genomes
2021The introduction of short-reads technologies ten years ago, significantly increased the number of available genomes. Generally, these assemblies are incomplete and fragmented, and only a few of them are at the chromosome-scale. More recently, Oxford Nanopore sequencing technology was commercialized with the promise to sequence long DNA fragments ...
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