Results 121 to 130 of about 128,901 (311)

Nicotinamide Reverses the Warburg Effect in CHO Cell Culture

Biotechnology and Bioengineering, EarlyView.
Abstract The Warburg effect, the preferential conversion of glucose‐derived pyruvat to lactate despite available oxygen, is a key feature of Chinese hamster ovary (CHO) cell culture. Lactate accumulation in recombinant protein‐producing cell culture is an inefficient usage of glucose, as well as being deleterious to cells.
James Morrissey, Ayca Cankorur‐Cetinkaya, Luigi Grassi, Annie J. Harwood‐Stamper, Jonathan Welsh, Ryte Poskute, Kasia Kozakowska‐McDonnell, Cleo Kontoravdi   +7 more
wiley   +1 more source

Interaction between cellular retinoic acid-binding protein II and histone hypoacetylation in renal cell carcinoma [PDF]

, 2008
Renal cell carcinoma is a rare but serious malignancy. Since a reduction in the level of retinoic acid receptor beta 2 (RARbeta2) expression in cancer cells due in part to histone hypoacetylation which is controlled by histone deacetylase (HD), the study
Wiwanitkit, Viroj
core   +1 more source

Genetic code expansion for chemosensing and chemical actuation of biological functions

Bulletin of the Korean Chemical Society, EarlyView.
Genetic code expansion (GCE) broadens the chemical repertoire for precise control of protein function in biological systems. This review highlights GCE‐based sensing and actuating systems that operate through selective interactions between noncanonical amino acids and chemical triggers.
Jieun Bae, Dong‐Hyun Kim, Minseob Koh
wiley   +1 more source

Controlled DNA compaction within chromatin: the tail-bridging effect

, 2005
We study the mechanism underlying the attraction between nucleosomes, the fundamental packaging units of DNA inside the chromatin complex. We introduce a simple model of the nucleosome, the eight-tail colloid, consisting of a charged sphere with eight ...
, , , , Boroudjerdi H., C Holm, F Mühlbacher, Frenkel D., H Schiessel, Mangenot S., McQuarrie D. A., Mühlbacher F., Odijk T., Schiessel H., Tse C.   +14 more
core   +1 more source

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source

Protein acetylation in archaea, bacteria, and eukaryotes [PDF]

, 2010
Proteins can be acetylated at the alpha-amino group of the N-terminal amino acid (methionine or the penultimate amino acid after methionine removal) or at the epsilon-amino group of internal lysines.
Lainio, Jarmo, Norberg Brorsson, Birgitta   +1 more
core  

Room‐Temperature Helix‐to‐Disc Conversion of Thia[6]helicene S,S‐Dioxides to Coronene via In Situ Phenoxide Anion Generation

Chemistry – A European Journal, EarlyView.
In situ phenoxide formation at the benzene terminus triggers room‐temperature conversion of thia[6]helicene S,S‐dioxides to coronene. The solubility contrast drives product precipitation, enabling isolation by simple filtration. This pericyclic annulation between the helical termini provides direct access to coronene‐type planar architectures ...
Kaito Seino, Takashi Murase
wiley   +1 more source

Bio‐Inspired Robust Non‐combustible Bioplastic with Superinsulated Energy Harvesting for Intelligent Firefighting

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study develops a novel non‐combustible chitosan‐based bioplastic (NCCB) via ethanol‐induced surface assembly. The material's inherent flame retardancy and thermally insulating, rough surface enable high‐performance TENGs. The NCCB‐TENG maintains stable output even when exposed to fire and exhibits dual sensitivity to temperature (25–200°C) and ...
Qilin Lu, Liying Zhang, Pengyun Zhang, Junjie Wang, Huamin Chen, Hanchen Wang   +5 more
wiley   +1 more source

Controlled Nanoarchitecture of Aligned Electrospinning Fiber Composite Electrolyte Based on Plant and Animal Biopolymers for Safe Na‐Ion Batteries

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Aligned Electrospun Composite Electrolyte. The resurgence of solid‐state Na+ battery, sustained through lithium deficiency and mounting costs, offers an auspicious alternative to solid‐state Li+ battery. This study introduces a nanoarchitectural approach that integrates electrospinning with a simple solution casting technique to develop a mechanically ...
Md. Mehadi Hassan, Brett Conners, Mojtaba Ebrahimian Mashhadi, Jinguang Hu, Xia Li, Qingye Lu   +5 more
wiley   +1 more source

Recent Advances in Pickering Emulsion Templated Phase Change Material Microcapsules: Design, Fabrication, and Multifunctional Applications

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Fabrication process of phase change microcapsules using a Pickering emulsion template method and their subsequent applications. The increasing demand for efficient thermal energy storage systems has driven the development of phase change material microcapsules (PCMMs), which provide high energy‐storage density, reversible phase change, and reduced ...
Ziyan Li, Jinsheng Sun, Kaihe Lv, Chaozheng Liu, Meichun Li   +4 more
wiley   +1 more source