The DEAD-box helicase Hlc regulates basal transcription and chromatin opening of stress-responsive genes. [PDF]
Jia R +5 more
europepmc +1 more source
The Role of Noncoding RNA in MGMT‐Positive Glioblastoma: A Narrative Review
ABSTRACT Glioblastoma (GBM) is the most aggressive primary malignant tumor of the central nervous system and is characterized by rapid progression, frequent recurrence, and poor survival outcomes. The current standard of care, comprising maximal safe surgical resection followed by radiotherapy with concomitant and adjuvant temozolomide (TMZ), has ...
Junfeng Zhao +6 more
wiley +1 more source
Measurement of ATP utilization in RNA unwinding and RNA chaperone activities by DEAD-box helicase proteins. [PDF]
Jarmoskaite I, Helmers AE, Russell R.
europepmc +1 more source
This graphical abstract illustrates the complete translational pipeline of Terminalia arjuna in modern phytomedicine and functional food development. It is rich in key bioactive compounds like arjunolic acid, arjungenin, flavonoids, and tannins which serve as the foundation for the plant's versatile medicinal uses and offers broad therapeutic benefits ...
Ishani Banerjee +5 more
wiley +1 more source
Discriminating activities of DEAD-Box Helicase 41 from myeloid malignancy-associated germline variants by genetic rescue. [PDF]
Kim JA +7 more
europepmc +1 more source
Two novel lytic Enterobacter phages, HHH and RZH, displayed targeted antibiofilm activity against MDR Enterobacter cloacae complex biofilms when combined with EDTA. Activity was strongest within a narrow low‐millimolar EDTA window, reducing biofilm biomass and viable burden, while higher EDTA concentrations shifted the interaction towards antagonism ...
Kashif Haq +4 more
wiley +1 more source
Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5. [PDF]
Saha S +11 more
europepmc +1 more source
Epitranscriptomics is understudied in bacteria but has the ability to modulate antimicrobial resistance, virulence and pathogenicity. Pitt et al. implement two cutting‐edge techniques: CRISPR interference and Nanopore direct RNA sequencing along with functional assays to study RNA modifications in Escherichia coli.
Miranda E. Pitt +8 more
wiley +1 more source
Pan-cancer analysis and breast cancer validation reveal DEAD-box helicase 23 as a crucial prognostic and immuno-biomarker. [PDF]
Ma H +7 more
europepmc +1 more source
Genetic Variation in DEAD-Box Helicase 20 as a Putative Marker of Recurrence in Propensity-Matched Colon Cancer Patients. [PDF]
Hobani YH +7 more
europepmc +1 more source

