Clinical and Molecular Features of BAP1‐Mutated Meningiomas: Case Series
ABSTRACT BRCA1‐associated protein 1 (BAP1)‐deficient meningiomas represent a clinically and molecularly distinct subgroup with variable histology and aggressive behavior that may not be fully captured by current grading criteria. The clinical spectrum of BAP1 alterations in meningiomas, including both somatic and germline contexts, remains incompletely
Ivan Pradilla +7 more
wiley +1 more source
Targeting the DNA Damage Response in Cancer
Targeting the DNA damage response (DDR) reshapes both tumor vulnerability and antitumor immunity. DNA lesions and DDR inhibitors can promote cytosolic nucleic‐acid sensing, antigen presentation, and immune activation, but can also induce adaptive immune escape.
Yihuan Qiao +4 more
wiley +1 more source
Probing Transcriptome-Wide RNA Structural Changes Dependent on the DEAD-box Helicase Dbp2. [PDF]
Lai YH, Tran EJ.
europepmc +1 more source
Chikungunya virus non-structural protein nsP3 interacts with Aedes aegypti DEAD-box helicase RM62F. [PDF]
Kumar R +10 more
europepmc +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Targeting Undruggable Protein Interactions with DNA Aptamers: Inhibition of the Interaction Between <i>Yersinia</i> Outer Protein M and Human DEAD-Box Helicase 3. [PDF]
Gök O, Uğurlu Ö, Özyurt C, Evran S.
europepmc +1 more source
Corrigendum: DEAD-Box Helicase DDX6 Facilitated RIG-I-Mediated Type-I Interferon Response to EV71 Infection. [PDF]
Zhang R +6 more
europepmc +1 more source
The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald +6 more
wiley +1 more source
African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylation. [PDF]
Fan J +10 more
europepmc +1 more source
DEAD-Box Helicase 27 Triggers Epithelial to Mesenchymal Transition by Regulating Alternative Splicing of Lipoma-Preferred Partner in Gastric Cancer Metastasis. [PDF]
Jin Y +9 more
europepmc +1 more source

