Results 121 to 130 of about 18,296 (185)

Aβ-42 Side Chain Deamidation at Q15 or N27 Modulates Protein Aggregation and Alters Microglial Cytokines and CD68. [PDF]

open access: yesACS Chem Neurosci
Griffin MN   +11 more
europepmc   +1 more source

DFT-based elucidation of asparagine deamidation in peptides

open access: yes, 2010
Asparagine (Asn) residues spontaneously – yet non-enzymatically – deamidate to form aspartate under physiological conditions, causing time-dependent changes in the conformation of proteins, limiting their lifetime [1].
De Sterck, Bart   +6 more
core  

A Combined Experimental-Theoretical Approach Unveils the Comprehensive Asn Deamidation Kinetics. [PDF]

open access: yesJ Am Chem Soc
De Sciscio ML   +8 more
europepmc   +1 more source

Studying the role of protein deamidation in neurodegenerative disease in proteome-wide scale

open access: yes, 2014
Deamidation had been associated with amyloid-β peptide and tau protein aggregation in Alzheimer’s disease. Our previous study detected dysregulation of membrane proteins in vascular dementia, and a review of the data revealed extensive deamidation of Na+/
Ang, Yi Lin
core  

A Practical Roadmap for Implementing the LC-MS-Based Multi-Attribute Method for Analysis of Therapeutic Proteins. [PDF]

open access: yesPharmaceuticals (Basel)
Guo J   +8 more
europepmc   +1 more source

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