Results 101 to 110 of about 18,296 (185)
Recently, an enzyme named protein-glutaminase (PG) has been identified as a new type of enzyme with significant potential for deamidation of food proteins.
Ruidan Qu +7 more
doaj +1 more source
Advances in Cytosolic dsRNA Sensing of Viral Infections
Activation of cytosolic dsRNA sensors by viral infection generates multiple outcomes. dsRNA generated during viral infection, either of viral origin or from endogenous sources, can activate multiple cytosolic dsRNA sensors. Activation of PKR critically induces protein translation shutdown via phosphorylation of eukaryotic translation initiation factor ...
Sofia Maceratessi, Natalia G. Sampaio
wiley +1 more source
Revisiting the effect of trypsin digestion buffers on artificial deamidation
Deamidation of asparagine and glutamine residues occurs spontaneously, is influenced by pH, temperature, and incubation time, and can be accelerated by adjacent amino acid residues.
Veth, Tim S. +2 more
core +1 more source
Working model of ERβ isoform signaling in human granulosa cells. Upon E2 binding, ERβ1 activates ERE‐dependent transcription and represses AP‐1 activity through Jun/Fos interactions. In contrast, ERβ2, ERβ4, and ERβ5 lack E2 binding and ERE activity but promote AP‐1‐dependent transcription and counteract ERβ1 repression, including after phosphorylation
Clémentine Marie +8 more
wiley +1 more source
Comparative physical evaluation of adhesive properties in modified gluten
The development of eco-friendly adhesives is essential to reduce reliance on petroleum-based products in the wood industry. In this study, wheat gluten was modified through enzymatic hydrolysis, heat treatment, and chemical reactions, including ...
Atefeh Mousavi, Javad Safaei-Ghomi
doaj +1 more source
Modeling Deamidation in Sheep α‑Keratin Peptides and Application to Archeological Wool Textiles
Deamidation of glutamine (Q) and asparagine (N) has been recognized as a marker of degradation and aging in ancient proteins. Using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) to study deamidation in wool ...
Caroline Solazzo (1861894) +8 more
core +1 more source
Effect of the (n +1) residue on peptide deamidation [PDF]
Deamidation occurs spontaneously in peptides and proteins [1]. Many reports show that deamidation has a substantial effect on protein structure, function and stability.
Félix, Jan +4 more
core
Collagen is the major component of skin, tendons, ligaments, teeth, and bones, it provides the framework that holds most multicellular animals together, and collagen type I constitutes the major fibrillar collagen of bone.
Pilar Perez Hurtado (2033869) +1 more
core +1 more source
Deamidation at N53 Causes SOD1 Structural Instability and Excess Zn Incorporation
Background/Objectives: Approximately 20% of familial ALS (fALS) cases are linked to mutations in Cu/Zn superoxide dismutase (SOD1). Through a gain function, SOD1 misfolding exerts a toxic effect on motor neurons, leading to their degradation and ALS ...
Eric Zanderigo +5 more
doaj +1 more source
Top-Down Study of β2-Microglobulin Deamidation
Although differentiation of the isomeric Asn deamidation products (Asp and isoAsp) at the peptide level by electron capture dissociation (ECD) has been well-established, isoAsp identification at the intact protein level remains a challenging task.
Xiaojuan Li (351842) +4 more
core +1 more source

