Results 81 to 90 of about 18,296 (185)
Oat protein solubility and emulsion properties improved by enzymatic deamidation
Oat protein produced by a dry milling process was enzymatically deamidated by a food-grade protein-glutaminase (PG), and the effects on structure, solubility and emulsifying properties of oat proteins were studied. The reactions were conducted at neutral
Sibakov, Juhani K. +5 more
core +1 more source
A well‐preserved 20 post‐conception week human brain was obtained and finely dissected into 18 anatomically distinct regions, including the pia mater. Each region underwent in‐depth proteomic analysis, encompassing both total protein content and post‐translational modifications.
S. Bandiera +9 more
wiley +1 more source
Examining collagen preservation through glutamine deamidation at Denisova Cave
The use of glutamine deamidation has been controversially proposed as a means of measuring relative decay in archeological bones using peptide mass fingerprinting data.
Shunkov, M. +13 more
core +1 more source
ABSTRACT Rationale Non‐reduced trypsin digestion of therapeutic antibodies can generate large disulfide‐linked peptide complexes that exhibit poor chromatographic and mass spectrometric performance. This limits the confident characterization of posttranslational modifications (PTMs) in specific antibody regions, such as the heavy‐chain constant region ...
Nanna Sofie Eskesen +10 more
wiley +1 more source
Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields
Canonical Y‐shaped antibodies recognize viral glycan shields through adaptive Fab assembly states shaped by glycan organization and somatic hypermutation. Structural analyses ofbroadly neutralizing antibodies VRC35 and VRC36 across glycoproteins of HIV‐1, influenza, SARS‐CoV‐2, and Lassa viruses reveal distinct Fab assembly states, spanning monovalent,
Jiaxuan Cheng +71 more
wiley +1 more source
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang +7 more
wiley +1 more source
Autolysin N617 Deamidation as a Molecular Target of Chelerythrine in Methicillin-Resistant
Objective Methicillin-resistant Staphylococcus aureus (MRSA) is a major clinical challenge due to its resistance to multiple antibiotics. Chelerythrine, a natural benzophenanthridine alkaloid, shows antibacterial activity against MRSA, but its precise ...
Jianhua Liao +4 more
doaj +1 more source
Visual Analysis of Research Progress on Protein Deamidation Based on CiteSpace Knowledge Map
In order to explore the research hotspots and development trends of protein deamidation, this paper systematically searched 133 Chinese literatures and 337 English literatures on protein deamidation in the CNKI and WOS databases, and the CiteSpace ...
LIU Xing-li +5 more
doaj +1 more source
Thermodynamics and Mechanism of the Deamidation of Sodium-Bound Asparagine
The deamidation of asparagine (Asn) residues is the most common type of spontaneous post-translational protein modification and plays a vital role in inflammation, protein transformation, apoptosis, aging, and a number of degenerative diseases.
P. B. Armentrout (1522729) +1 more
core +1 more source

