Results 81 to 90 of about 18,296 (185)

Oat protein solubility and emulsion properties improved by enzymatic deamidation

open access: yes, 2015
Oat protein produced by a dry milling process was enzymatically deamidated by a food-grade protein-glutaminase (PG), and the effects on structure, solubility and emulsifying properties of oat proteins were studied. The reactions were conducted at neutral
Sibakov, Juhani K.   +5 more
core   +1 more source

A posttranslational proteomic survey of a single anatomically preserved human 20‐week postconception brain

open access: yesJournal of Anatomy, EarlyView.
A well‐preserved 20 post‐conception week human brain was obtained and finely dissected into 18 anatomically distinct regions, including the pia mater. Each region underwent in‐depth proteomic analysis, encompassing both total protein content and post‐translational modifications.
S. Bandiera   +9 more
wiley   +1 more source

Examining collagen preservation through glutamine deamidation at Denisova Cave

open access: yes, 2021
The use of glutamine deamidation has been controversially proposed as a means of measuring relative decay in archeological bones using peptide mass fingerprinting data.
Shunkov, M.   +13 more
core   +1 more source

Automated Multienzyme Digestion Workflows for Confident Characterization of Challenging Posttranslational Modifications in Therapeutic Antibodies by LC–MS/MS

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 21, 15 November 2026.
ABSTRACT Rationale Non‐reduced trypsin digestion of therapeutic antibodies can generate large disulfide‐linked peptide complexes that exhibit poor chromatographic and mass spectrometric performance. This limits the confident characterization of posttranslational modifications (PTMs) in specific antibody regions, such as the heavy‐chain constant region ...
Nanna Sofie Eskesen   +10 more
wiley   +1 more source

Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
Canonical Y‐shaped antibodies recognize viral glycan shields through adaptive Fab assembly states shaped by glycan organization and somatic hypermutation. Structural analyses ofbroadly neutralizing antibodies VRC35 and VRC36 across glycoproteins of HIV‐1, influenza, SARS‐CoV‐2, and Lassa viruses reveal distinct Fab assembly states, spanning monovalent,
Jiaxuan Cheng   +71 more
wiley   +1 more source

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang   +7 more
wiley   +1 more source

Autolysin N617 Deamidation as a Molecular Target of Chelerythrine in Methicillin-Resistant

open access: yesNatural Product Communications
Objective Methicillin-resistant Staphylococcus aureus (MRSA) is a major clinical challenge due to its resistance to multiple antibiotics. Chelerythrine, a natural benzophenanthridine alkaloid, shows antibacterial activity against MRSA, but its precise ...
Jianhua Liao   +4 more
doaj   +1 more source

Visual Analysis of Research Progress on Protein Deamidation Based on CiteSpace Knowledge Map

open access: yesLiang you shipin ke-ji
In order to explore the research hotspots and development trends of protein deamidation, this paper systematically searched 133 Chinese literatures and 337 English literatures on protein deamidation in the CNKI and WOS databases, and the CiteSpace ...
LIU Xing-li   +5 more
doaj   +1 more source

Thermodynamics and Mechanism of the Deamidation of Sodium-Bound Asparagine

open access: yes, 2016
The deamidation of asparagine (Asn) residues is the most common type of spontaneous post-translational protein modification and plays a vital role in inflammation, protein transformation, apoptosis, aging, and a number of degenerative diseases.
P. B. Armentrout (1522729)   +1 more
core   +1 more source

Additional file 1 of Deamidation-related blood biomarkers show promise for early diagnostics of neurodegeneration

open access: yes, 2022
Additional file 1: Table S1.
Jijing Wang (15217891)   +8 more
core   +1 more source

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