Results 111 to 120 of about 18,296 (185)

The Unified Theory of Neurodegeneration Pathogenesis Based on Axon Deamidation

Until now, neurodegenerative diseases like Alzheimer’s and Parkinson’s have been studied separately in biochemistry and therapeutic drug development, and no causal link has ever been established between them.
Davis Joseph
core   +1 more source

HSV1 Pulls the Deamidation tRIGger

, 2016
Viruses have evolved a remarkable array of strategies to escape the host's innate immune responses. In this issue of Cell Host & Microbe, Zhao et al.
Garcin, Dominique, Garcin D
core   +1 more source

Racemization of an Asparagine Residue during Peptide Deamidation

, 2016
The Asn residue in the pentapeptide Asn-Gln-Asn-Glu-Gly undergoes racemization at the Cα center in the course of deamidation of this residue through a succinimide intermediate. The succinimide intermediate is known to racemize at the corresponding center,
Ronald T. Borchardt (2263435), Richard L. Schowen (2263438), Bei Li (90587), David VanderVelde (1814314), Elizabeth M. Topp (1320795)   +4 more
core   +1 more source

Modulation of surface charges of napin by enzymatic deamidation to improve its techno-functional properties

Napin is a major seed storage protein found in plants of the Brassica family and has an isoelectric point of 9–11, which may complicate its application in foods. Our aim was to reduce the isoelectric point of napin by enzymatic deamidation.
Poojary, Mahesha M., Engholm-Keller, Kasper, Lund, Marianne N., Karalia, Shivani, Raak, Norbert   +4 more
core   +1 more source

H1N76/77 deamidation facilitates chromatin remodelling and genome stability during DNA damage repair

Clinical and Translational Medicine
Chromatin relaxation is a permissiven progress for DNA repair through enabling repair factors to access the damaged DNA. Linker histone H1 is important in maintaining chromatin compaction under physiological state.
Tingting Feng, Mengyan Li, Chenmiao Hu, Yuan Tian, Wei‐Guo Zhu   +4 more
doaj   +1 more source

Selective Deamidation of Ribonuclease A

, 1993
Selective deamidation of proteins and peptides is a reaction of great interest, whether it has physiological significance as in protein aging, or occurs as a disturbing event in the preparation of natural or recombinant proteins.
MAZZARELLA, LELIO, D'ALESSIO, GIUSEPPE, Ciardiello M.A., DI DONATO, ALBERTO, de Nigris M., PICCOLI, RENATA   +5 more
core  

Raman spectroscopic determination of extent of deamidation of food proteins

, 2005
Soy protein isolates, egg white protein and whey protein isolates are utilized widely in the food industry as functional ingredients. Deamidation has been reported to improve the functional properties of these three protein products and other food ...
Phillips, DL, Wong, HW, Ma, CY
core  

Study of spontaneous deamidation of camel's milk α-lactalbumin

, 2014
International audienceMany proteins are susceptible, both in vivo and in vitro, to non enzymatic deamidation that can lead to alterations in their structure and biological functions.
Girardet, Jean-Michel, Mati, Abderrahmane, Si Ahmed Zennia, Saliha   +2 more
core  

Rapid Antibody Structural Characterization and Quantification via Microdroplet Trypsin Digestion. [PDF]

J Am Soc Mass Spectrom
Xiao M, Yang Y, Schladebeck A, Lau J, Knierman M, Zhao H, Qiu X, Luo K, Gunawardena HP, Chen H.   +9 more
europepmc   +1 more source

Age-Related Lens Membrane Composition and N101D Deamidation Modulate αA-Crystallin Membrane Interactions Relevant to Cataract. [PDF]

Invest Ophthalmol Vis Sci
Hazen P, Anderson J, Kalkat N, Aryal B, Khadka NK, Mainali L.   +5 more
europepmc   +1 more source