Efficacy of adjusted weight-based dosing of desmopressin (1-deamino-8-d-arginine vasopressin in type 1 von Willebrand disease. [PDF]
Introduction VonWillebrand disease (VWD), the most common inherited bleeding disorder, is a heterogeneous condition caused by a deficiency or defect in von Willebrand factor (VWF).
Seaman CD.
europepmc +4 more sources
Pharmacokinetics, pharmacodynamics, long‐term efficacy and safety of oral 1‐deamino‐8‐d‐arginine vasopressin in adult patients with central diabetes insipidus [PDF]
1. The pharmacokinetics and pharmacodynamics of intranasal (IN) and oral 1-deamino-8-D-arginine vasopressin (DDAVP) were compared in 10 Chinese adults with central diabetes insipidus previously controlled on IN DDAVP.
Karen S.L. Lam+5 more
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[1-Deamino-4-Cyclohexylalanine] Arginine Vasopressin: A Potent and Specific Agonist for Vasopressin V1b Receptors [PDF]
To date, there are no vasopressin (VP) agonists that exhibit a high affinity and selectivity for the VP V1b receptor with respect to the V1a, V2, and oxytocin receptors.
Sylvain Derick+11 more
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Desmopressin use in major cardiac surgery is associated with renal impairment: a retrospective single-center analysis [PDF]
Background Desmopressin acetate (1-deamino-8-d-arginine vasopressin—DDAVP) is a analogue of the antidiuretic hormone vasopressin. DDAVP is suggested to reduce bleeding after cardiac surgery using cardiopulmonary bypass.
Andreas Koköfer+5 more
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Cyclic-AMP regulates postnatal development of neural and behavioral responses to NaCl in rats. [PDF]
During postnatal development rats demonstrate an age-dependent increase in NaCl chorda tympani (CT) responses and the number of functional apical amiloride-sensitive epithelial Na+ channels (ENaCs) in salt sensing fungiform (FF) taste receptor cells ...
Jie Qian+12 more
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In order to elucidate the mechanism(s) responsible for the prolonged antidiuretic activity of 1-deamino-[8-D-arginine]-vasopressin (dDAVP), antidiuretic activities of dDAVP and arginine vasopressin (AVP) were determined in the rat following either oral ...
Kuniaki Matsui+6 more
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Central Adrenal Insufficiency and Diabetes Insipidus Misdiagnosed as Severe Depression [PDF]
A 68 year-old Japanese man, who had been suffering from immobilization and disuse syndrome, was admitted to our hospital for evaluation of polyuria with polyposia, hyponatremia and low blood pressure.
Naoki Hiroi+4 more
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Safety and efficacy of desmopressin (DDAVP) in preventing hematoma expansion in intracranial hemorrhage associated with antiplatelet drugs use: A systematic review and metaanalysis. [PDF]
Abstract Introduction One of the most serious complications associated with antiplatelet agents is antiplatelet‐associated intracranial hemorrhage (AA‐ICH). Desmopressin is a synthetic antidiuretic hormone (ADH) analog. It has been linked to improving patient outcomes in antiplatelet‐induced intracranial hemorrhage.
Shahzad F+10 more
europepmc +2 more sources
Vasopressin Analog [V4Q5]dDAVP Exerts Cooperative Anticancer Effects in Combination With Low-Dose 5-Fluorouracil on Aggressive Colorectal Cancer Models. [PDF]
Background: Colorectal cancer (CRC) is a leading cause of cancerassociated mortality worldwide. Despite being an essential component of systemic chemotherapy for advanced CRC, 5-fluorouracil (5-FU) clinical use has severe limitations, such as high ...
Sobol NT+4 more
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Acquired von Willebrand syndrome in a patient with monoclonal gammopathy of unknown significance: A case report. [PDF]
Abstract Monoclonal gammopathy of uncertain significance associated acquired von Willebrand syndrome is a serious bleeding condition driven by immunological clearance of von Willebrand factor and has limited treatment options. We present a patient who achieved durable remission through eradication of the monoclonal paraprotein with clonal directed ...
Gupta G+3 more
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