Results 111 to 120 of about 10,693,133 (406)

Inhibition of ACSL4 ameliorates tubular ferroptotic cell death and protects against fibrotic kidney disease [PDF]

open access: gold, 2023
Yue Dai   +8 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes

open access: yesCell Reports, 2015
Ubiquitination and deubiquitination are crucial for assembly and disassembly of signaling complexes. LUBAC-generated linear (M1) ubiquitin is important for signaling via various immune receptors.
Peter Draber   +13 more
doaj   +1 more source

Apnoea and bradycardia during epileptic seizures: relation to sudden death in epilepsy. [PDF]

open access: bronze, 1996
Lina Nashef   +5 more
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

‘Technology in end-of-life care is very important’: the view of nurses regarding technology and end-of-life care

open access: yesBMC Nursing
Background Globally, digital transformation has been sweeping through healthcare in recent years. Reflecting this global change, Australia’s health and social care sector is also undergoing rapid digitalisation.
Priyanka Vandersman, Jennifer Tieman
doaj   +1 more source

Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair

open access: yesNature Communications, 2017
The role of annexins in cell membrane repair is largely undefined. Here the authors use a model lipid bilayer to show that annexin A4 induces curvature at the membrane free edge and annexin A6 induces constriction force, and find that both annexins are ...
Theresa Louise Boye   +7 more
doaj   +1 more source

The Death of Reliance [PDF]

open access: yes, 1996
In the mid-1970s, it was an article offaith that contract was not properly conceived as a means by which persons could, by their own choice, make law for themselves to govern their relations.
Barnett, Randy E.
core   +1 more source

Cell Death by Entosis: Triggers, Molecular Mechanisms and Clinical Significance [PDF]

open access: gold, 2022
Mostafa Kianfar   +4 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

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