Results 11 to 20 of about 3,226,550 (274)

Bad Apples, Bad Barrel: Exploring Institutional Responses to Child Sexual Abuse by Catholic Clergy in Australia

open access: yesInternational Journal for Crime, Justice and Social Democracy, 2015
This paper considers constructions of institutional culture and power in the cover-up of child sexual abuse (CSA) by clergy in the Roman Catholic Church of Australia.
Jodi Death
doaj   +1 more source

Death doula working practices and models of care: the views of death doula training organisations

open access: yesBMC Palliative Care, 2023
Background The role of death doula has emerged in recent years, arguably as a result of overwhelming demands on carers, healthcare professionals and service providers in end-of-life care.
Deb Rawlings   +3 more
doaj   +1 more source

Entosis: The emerging face of non-cell-autonomous type IV programmed death

open access: yesBiomedical Journal, 2017
The present review summarizes recent experimental evidences about the existence of the non-cell-autonomous death entosis in physiological and pathophysiological contexts, discusses some aspects of this form of cell death, including morphological ...
Isabelle Martins   +10 more
doaj   +1 more source

Copy Number Variation and Structural Genomic Findings in 116 Cases of Sudden Unexplained Death between 1 and 28 Months of Age

open access: yesAdvanced Genetics, 2023
In sudden unexplained death in pediatrics (SUDP) the cause of death is unknown despite an autopsy and investigation. The role of copy number variations (CNVs) in SUDP has not been well‐studied. Chromosomal microarray (CMA) data are generated for 116 SUDP
Catherine A. Brownstein   +14 more
doaj   +1 more source

PTEN-lipid Binding Assay

open access: yesBio-Protocol, 2013
The lipid and protein interactions are an integral and important part of many cellular signaling pathways. The understanding of the selective and specific interaction of the given lipid molecule with the target protein is required for studying cellular ...
Sridhar Kavela   +2 more
doaj   +1 more source

Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities [PDF]

open access: yesEur. J. Epidemiol. 36, 545--558 (2021), 2021
Factors such as non-uniform definitions of mortality, uncertainty in disease prevalence, and biased sampling complicate the quantification of fatality during an epidemic. Regardless of the employed fatality measure, the infected population and the number of infection-caused deaths need to be consistently estimated for comparing mortality across regions.
arxiv   +1 more source

Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics

open access: yesOncoImmunology, 2017
The expression “immunogenic cell death” (ICD) refers to a functionally unique form of cell death that facilitates (instead of suppressing) a T cell-dependent immune response specific for dead cell-derived antigens. ICD critically relies on the activation
Abhishek D. Garg   +8 more
doaj   +1 more source

Macrophage biology plays a central role during ionizing radiation-elicited tumor response

open access: yesBiomedical Journal, 2017
Radiation therapy is one of the major therapeutic modalities for most solid tumors. The anti-tumor effect of radiation therapy consists of the direct tumor cell killing, as well as the modulation of tumor microenvironment and the activation of immune ...
Qiuji Wu   +5 more
doaj   +1 more source

Cell-in-cell structure mediates in-cell killing suppressed by CD44

open access: yesCell Discovery, 2022
Penetration of immune cells into tumor cells was believed to be immune-suppressive via cell-in-cell (CIC) mediated death of the internalized immune cells.
Yan Su   +17 more
doaj   +1 more source

Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis

open access: yesCell Death and Disease, 2021
Ferroptosis is a type of regulated cell death characterized by ROS accumulation and devastating lipid peroxidation (LPO). The role of acid sphingomyelinase (ASM), a key enzyme in sphingolipid metabolism, in the induction of apoptosis has been studied ...
Faisal Thayyullathil   +6 more
doaj   +1 more source

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