Results 21 to 30 of about 8,379,745 (360)

“They want you to know who they really are inside of the old visage”—biographical storytelling as a methodological tool to explore emotional challenges in old age

open access: yesBMC Geriatrics, 2023
Background Growing older is often associated with resilience, contentedness and inner growth. Older people however are also at risk of confronting unique emotional challenges as a result of varied ageing-related experiences.
Chao Fang, Alastair Comery, Sam Carr
doaj   +1 more source

Controls on the spatial distribution of oceanic δ13CDIC [PDF]

open access: yes, 2013
We describe the design and evaluation of a large ensemble of coupled climate–carbon cycle simulations with the Earth system model of intermediate complexity GENIE.
Death, R. M.   +5 more
core   +3 more sources

Adverse effects of prenatal tobacco smoke exposure on biological parameters of the developing brainstem

open access: yesNeurobiology of Disease, 2005
We aimed to study the consequences of chronic exposure to tobacco smoke in utero on the morphological and functional maturation of the brainstem by comparing stillbirths of smoker mothers versus nonsmoker mothers.
Anna Maria Lavezzi   +2 more
doaj   +1 more source

Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis

open access: yesCell Death and Disease, 2021
Ferroptosis is a type of regulated cell death characterized by ROS accumulation and devastating lipid peroxidation (LPO). The role of acid sphingomyelinase (ASM), a key enzyme in sphingolipid metabolism, in the induction of apoptosis has been studied ...
Faisal Thayyullathil   +6 more
doaj   +1 more source

Lysosomal Changes in Mitosis

open access: yesCells, 2022
The recent discovery demonstrating that the leakage of cathepsin B from mitotic lysosomes assists mitotic chromosome segregation indicates that lysosomal membrane integrity can be spatiotemporally regulated.
Jonathan Stahl-Meyer   +4 more
doaj   +1 more source

Ferroptosis: friend or foe in cancer immunotherapy?

open access: yesOncoImmunology, 2023
Ferroptosis has gained interest due to it immunogenicity and the higher sensitivity of cancer cells to it. However, it was recently shown that ferroptosis in tumor-associated neutrophils leads to immunosuppression and negatively impacts therapy. Here, we
Robin Demuynck   +3 more
doaj   +1 more source

Cell Death [PDF]

open access: yesInternational Journal of Cell Biology, 2014
N ...
GIAMPIETRI, Claudia   +2 more
openaire   +5 more sources

Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines

open access: yesCell Death and Disease, 2021
Sorafenib, a protein kinase inhibitor approved for the treatment of hepatocellular carcinoma and advanced renal cell carcinoma, has been repeatedly reported to induce ferroptosis by possibly involving inhibition of the cystine/glutamate antiporter, known
Jiashuo Zheng   +5 more
doaj   +1 more source

Life at the end of life: beliefs about individual life after death and "good death" models - a qualitative study [PDF]

open access: yes, 2003
BACKGROUND: Different ideas of "good death" may influence the effectiveness of end-of-life care in patients with different ethos. This study aimed to identify the influence of believing in individual life after death on "good death" models. METHODS: Semi
Boeri, Paolo   +3 more
core   +3 more sources

Definition of Sudden Infant Death and Sudden Intrauterine Unexpected Death Syndromes (SIDS and SIUDS) with Regard to the Anatomo-Pathological Examination

open access: yesFrontiers in Pediatrics, 2016
Crib death, or sudden infant death syndrome (SIDS), is the most frequent form of death in the first year of life, striking one baby in every 1,700–2,000.
Giulia Ottaviani
doaj   +1 more source

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