Results 21 to 30 of about 3,226,550 (274)

Lysosomal Changes in Mitosis

open access: yesCells, 2022
The recent discovery demonstrating that the leakage of cathepsin B from mitotic lysosomes assists mitotic chromosome segregation indicates that lysosomal membrane integrity can be spatiotemporally regulated.
Jonathan Stahl-Meyer   +4 more
doaj   +1 more source

Correlations and forecast of death tolls in the Syrian conflict [PDF]

open access: yesScientific Reports 7, 15737 (2017), 2016
The Syrian civil war has been ongoing since 2011 and has already caused thousands of deaths. The analysis of death tolls helps to understand the dynamics of the conflict and to better allocate resources to the affected areas. In this article, we use information on the daily number of deaths to study temporal and spatial correlations in the data, and ...
arxiv   +1 more source

“They want you to know who they really are inside of the old visage”—biographical storytelling as a methodological tool to explore emotional challenges in old age

open access: yesBMC Geriatrics, 2023
Background Growing older is often associated with resilience, contentedness and inner growth. Older people however are also at risk of confronting unique emotional challenges as a result of varied ageing-related experiences.
Chao Fang, Alastair Comery, Sam Carr
doaj   +1 more source

Ferroptosis: friend or foe in cancer immunotherapy?

open access: yesOncoImmunology, 2023
Ferroptosis has gained interest due to it immunogenicity and the higher sensitivity of cancer cells to it. However, it was recently shown that ferroptosis in tumor-associated neutrophils leads to immunosuppression and negatively impacts therapy. Here, we
Robin Demuynck   +3 more
doaj   +1 more source

Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines

open access: yesCell Death and Disease, 2021
Sorafenib, a protein kinase inhibitor approved for the treatment of hepatocellular carcinoma and advanced renal cell carcinoma, has been repeatedly reported to induce ferroptosis by possibly involving inhibition of the cystine/glutamate antiporter, known
Jiashuo Zheng   +5 more
doaj   +1 more source

Kinetic Monte Carlo study of the type1/type 2 choice in apoptosis elucidates selective killing of cancer cells under death ligand induction [PDF]

open access: yesOJApo 4 (2015) 22-39, 2015
Death ligand mediated apoptotic activation is a mode of programmed cell death that is widely used in cellular and physiological situations. Interest in studying death ligand induced apoptosis has increased due to the promising role of recombinant soluble forms of death ligands (mainly recombinant TRAIL) in anti-cancer therapy.
arxiv   +1 more source

Definition of Sudden Infant Death and Sudden Intrauterine Unexpected Death Syndromes (SIDS and SIUDS) with Regard to the Anatomo-Pathological Examination

open access: yesFrontiers in Pediatrics, 2016
Crib death, or sudden infant death syndrome (SIDS), is the most frequent form of death in the first year of life, striking one baby in every 1,700–2,000.
Giulia Ottaviani
doaj   +1 more source

Excess death rates for Republicans and Democrats during the COVID-19 pandemic [PDF]

open access: yesarXiv, 2022
Political affiliation has emerged as a potential risk factor for COVID-19, amid evidence that Republican-leaning counties have had higher COVID-19 death rates than Democrat-leaning counties and evidence of a link between political party affiliation and vaccination views.
arxiv  

Quantum manifestations of homogeneous and inhomogeneous oscillation suppression states [PDF]

open access: yesPhys. Rev. E 102, 062205 (2020), 2020
We study the quantum manifestations of homogeneous and inhomogeneous oscillation suppression states in coupled identical quantum oscillators. We consider quantum van der Pol oscillators coupled via weighted mean-field diffusive coupling and using the formalism of open quantum system we show that depending upon the coupling and the density of mean-field,
arxiv   +1 more source

Long-range enhancement of N501Y-endowed mouse infectivity of SARS-CoV-2 by the non-RBD mutations of Ins215KLRS and H655Y

open access: yesBiology Direct, 2022
Background Rodents, such as mice, are vulnerable targets, and potential intermediate hosts, of SARS-CoV-2 variants of concern, including Alpha, Beta, Gamma, and Omicron.
Yichao Zhu   +9 more
doaj   +1 more source

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