Results 21 to 30 of about 3,226,550 (274)
The recent discovery demonstrating that the leakage of cathepsin B from mitotic lysosomes assists mitotic chromosome segregation indicates that lysosomal membrane integrity can be spatiotemporally regulated.
Jonathan Stahl-Meyer+4 more
doaj +1 more source
Correlations and forecast of death tolls in the Syrian conflict [PDF]
The Syrian civil war has been ongoing since 2011 and has already caused thousands of deaths. The analysis of death tolls helps to understand the dynamics of the conflict and to better allocate resources to the affected areas. In this article, we use information on the daily number of deaths to study temporal and spatial correlations in the data, and ...
arxiv +1 more source
Background Growing older is often associated with resilience, contentedness and inner growth. Older people however are also at risk of confronting unique emotional challenges as a result of varied ageing-related experiences.
Chao Fang, Alastair Comery, Sam Carr
doaj +1 more source
Ferroptosis: friend or foe in cancer immunotherapy?
Ferroptosis has gained interest due to it immunogenicity and the higher sensitivity of cancer cells to it. However, it was recently shown that ferroptosis in tumor-associated neutrophils leads to immunosuppression and negatively impacts therapy. Here, we
Robin Demuynck+3 more
doaj +1 more source
Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines
Sorafenib, a protein kinase inhibitor approved for the treatment of hepatocellular carcinoma and advanced renal cell carcinoma, has been repeatedly reported to induce ferroptosis by possibly involving inhibition of the cystine/glutamate antiporter, known
Jiashuo Zheng+5 more
doaj +1 more source
Kinetic Monte Carlo study of the type1/type 2 choice in apoptosis elucidates selective killing of cancer cells under death ligand induction [PDF]
Death ligand mediated apoptotic activation is a mode of programmed cell death that is widely used in cellular and physiological situations. Interest in studying death ligand induced apoptosis has increased due to the promising role of recombinant soluble forms of death ligands (mainly recombinant TRAIL) in anti-cancer therapy.
arxiv +1 more source
Crib death, or sudden infant death syndrome (SIDS), is the most frequent form of death in the first year of life, striking one baby in every 1,700–2,000.
Giulia Ottaviani
doaj +1 more source
Excess death rates for Republicans and Democrats during the COVID-19 pandemic [PDF]
Political affiliation has emerged as a potential risk factor for COVID-19, amid evidence that Republican-leaning counties have had higher COVID-19 death rates than Democrat-leaning counties and evidence of a link between political party affiliation and vaccination views.
arxiv
Quantum manifestations of homogeneous and inhomogeneous oscillation suppression states [PDF]
We study the quantum manifestations of homogeneous and inhomogeneous oscillation suppression states in coupled identical quantum oscillators. We consider quantum van der Pol oscillators coupled via weighted mean-field diffusive coupling and using the formalism of open quantum system we show that depending upon the coupling and the density of mean-field,
arxiv +1 more source
Background Rodents, such as mice, are vulnerable targets, and potential intermediate hosts, of SARS-CoV-2 variants of concern, including Alpha, Beta, Gamma, and Omicron.
Yichao Zhu+9 more
doaj +1 more source