Results 51 to 60 of about 88,974,747 (261)

Pancreas Procurement and Preservation for Islet Transplantation: Personal Considerations

Journal of Transplantation, 2011
Pancreatic islet transplantation is a promising option for the treatment of type 1 diabetic patients. After the successful demonstration of the Edmonton protocol, islet transplantation has advanced significantly on several fronts, including improved ...
Hirofumi Noguchi
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Analysis of clinical factors affecting corneal endothelial cell density in eye bank donors

Frontiers in Ophthalmology
PurposeTo systematically analyze factors influencing corneal endothelial cell density (ECD) in eye bank donors and provide robust evidence for optimizing donor screening strategies.MethodsA retrospective analysis was conducted on 1438 corneas from 782 ...
Lan Yu, Wei Ming, Shangcao Wu, Qiaoqiao Dong, Jingwei Li, Jiao Qin, Qingyan Zeng   +6 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Successful 3-day lung preservation using a cyclic normothermic ex vivo lung perfusion strategy

EBioMedicine, 2022
Summary: Background: Cold static preservation (CSP) at higher temperatures (10°C) has been recently shown as an optimal strategy up to 24-36h of preservation. Here, we hypothesized that alternating 10°C static storage with cycles of normothermic ex vivo
Aadil Ali, Antti I. Nykanen, Erika Beroncal, Edson Brambate, Andrea Mariscal, Vinicius Michaelsen, Aizhou Wang, Mitsuaki Kawashima, Rafaela V.P. Ribeiro, Yu Zhang, Eddy Fan, Laurent Brochard, Jonathan Yeung, Tom Waddell, Mingyao Liu, Ana C. Andreazza, Shaf Keshavjee, Marcelo Cypel   +17 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Arkansas Coalition to Abolish the Death Penalty records

, 1978
This collection contains ACADP correspondence, memos, newsletters, board minutes, news clippings, and brochures.
Arkansas Coalition to Abolish the Death Penalty
core   +1 more source

Complete preservation of mitral valve apparatus versus posterior leaflet preservation only during mitral valve replacement for rheumatic mitral regurgitation

Journal of Medicine in Scientific Research, 2020
Objectives In the present study we investigated whether preservation of both leaflets (anterior and Posterior with subvalvular apparatus) is superior to preservation of the posterior leaflet Alone.
Maged M Kisho
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source