Results 1 to 10 of about 5,170 (138)
Memantine, Simvastatin, and Epicatechin Inhibit 7-Ketocholesterol-induced Apoptosis in Retinal Pigment Epithelial Cells But Not Neurosensory Retinal Cells In Vitro. [PDF]
J Ophthalmic Vis Res, 2020 Purpose: 7-ketocholesterol (7kCh), a natural byproduct of oxidation in lipoprotein deposits is implicated in the pathogenesis of diabetic retinopathy and age-related macular degeneration (AMD).
Neekhra A +11 more
europepmc +7 more sources
Indian Journal of Ophthalmology, 2013 Purpose: To evaluate the effect of bevacizumab on the mitochondrial function of human retinal pigment epithelial (ARPE-19), rat neurosensory retinal (R28) and human microvascular endothelial (HMVEC) cells in culture.
Saurabh Luthra +7 more
doaj +5 more sources
On the Wrong Track: Alterations of Ciliary Transport in Inherited Retinal Dystrophies
Frontiers in Cell and Developmental Biology, 2021 Ciliopathies are a group of heterogeneous inherited disorders associated with dysfunction of the cilium, a ubiquitous microtubule-based organelle involved in a broad range of cellular functions. Most ciliopathies are syndromic, since several organs whose
Laura Sánchez-Bellver +6 more
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BMC Ophthalmology, 2022 Background The retinal pigment epithelium (RPE), a layer of pigmented cells that lies between the neurosensory retina and the underlying choroid, plays a critical role in maintaining the functional integrity of photoreceptor cells and in mediating ...
Sydney M. Galindez +2 more
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Vision and retina evolution: How to develop a retina
IBRO Neuroscience Reports, 2022 Early in vertebrate evolution, a single homeobox (Hox) cluster in basal chordates was quadrupled to generate the Hox gene clusters present in extant vertebrates.
Bernd Fritzsch, Paul R. Martin
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Delhi Journal of Ophthalmology, 2021 Combined hamartoma of retina and retinal pigment epithelium (CHRRPE) is a benign tumor located at the posterior pole. The pathogenesis of the lesion is unknown however some authors propose that the tumor may arise from undifferentiated ectopic progenitor
Monika Kapoor +4 more
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Comparison of CRISPR/Cas Endonucleases for in vivo Retinal Gene Editing
Frontiers in Cellular Neuroscience, 2020 CRISPR/Cas has opened the prospect of direct gene correction therapy for some inherited retinal diseases. Previous work has demonstrated the utility of adeno-associated virus (AAV) mediated delivery to retinal cells in vivo; however, with the expanding ...
Fan Li +23 more
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In vivo imaging of the outer retina after an autologous neurosensory retinal free flap transplantation for a refractory macular hole closure. [PDF]
J Med Case RepJohnson DA, Doble N, Ohr MP, Choi SS.
europepmc +2 more sources
Бюллетень сибирской медицины, 2013 The method of spontaneous and induced luminol -dependent chemiluminescence in homogenates of rat retinas OXYS registered increase in the generation of free radicals against decrease in total antioxidant activity.
A. A. Zhdankina +6 more
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Effects of a high-fat, high-carbohydrate diet on the retina of young and old rats
Бюллетень сибирской медицины, 2023 Aim. To study the effect of a high-fat, high-carbohydrate diet on retinal morphology of young and old rats in the experiment.Materials and methods. The study was carried out on male Wistar rats aged 60 and 450 days at the beginning of the experiment. The
S. V. Logvinov +5 more
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