Results 11 to 20 of about 5,017 (139)
Comparison of CRISPR/Cas Endonucleases for in vivo Retinal Gene Editing
Frontiers in Cellular Neuroscience, 2020 CRISPR/Cas has opened the prospect of direct gene correction therapy for some inherited retinal diseases. Previous work has demonstrated the utility of adeno-associated virus (AAV) mediated delivery to retinal cells in vivo; however, with the expanding ...
Fan Li +23 more
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Бюллетень сибирской медицины, 2013 The method of spontaneous and induced luminol -dependent chemiluminescence in homogenates of rat retinas OXYS registered increase in the generation of free radicals against decrease in total antioxidant activity.
A. A. Zhdankina +6 more
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Effects of a high-fat, high-carbohydrate diet on the retina of young and old rats
Бюллетень сибирской медицины, 2023 Aim. To study the effect of a high-fat, high-carbohydrate diet on retinal morphology of young and old rats in the experiment.Materials and methods. The study was carried out on male Wistar rats aged 60 and 450 days at the beginning of the experiment. The
S. V. Logvinov +5 more
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Microfluidic and Microscale Assays to Examine Regenerative Strategies in the Neuro Retina
Micromachines, 2020 Bioengineering systems have transformed scientific knowledge of cellular behaviors in the nervous system (NS) and pioneered innovative, regenerative therapies to treat adult neural disorders.
Maribel Vazquez
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Caspase-8, -12, and -3 Activation by 7-Ketocholesterol in Retinal Neurosensory Cells
Investigative Opthalmology & Visual Science, 2007 To determine the caspase pathways involved with 7-ketocholesterol (7kCh)-induced apoptosis in rat R28 cells.R28 cells were exposed to 7kCh with or without low-density lipoprotein (LDL) and z-VAD-fmk, a pan-caspase inhibitor. Cell viability was measured by a trypan blue dye exclusion assay.
Aneesh, Neekhra +6 more
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NLRP3 and autophagy in retinal ganglion cell inflammation in age-related macular degeneration: potential therapeutic implications [PDF]
International Journal of OphthalmologyRetinal degenerative diseases were a large group of diseases characterized by the primary death of retinal ganglion cells (RGCs). Recent studies had shown an interaction between autophagy and nucleotide-binding oligomerization domain-like receptor 3 ...
Xiao-Li Wang +3 more
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International Journal for Parasitology: Parasites and Wildlife, 2018 The eye represents an immune privileged organ where parasites can escape host reactions. This study provides the first systematic evidence of the pathology associated with Diplostomum sp. infection in the eye retina of fish (i.e.
F. Padrós, R. Knudsen, I. Blasco-Costa
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Investigative Opthalmology & Visual Science, 2017 We investigated whether subthreshold retinal phototherapy (SRPT) was associated with recruitment of bone marrow (BM)-derived cells to the neurosensory retina (NSR) and RPE layer.GFP chimeric mice and wild-type (WT) mice were subjected to SRPT using a slit-lamp infrared laser.
Caballero, Sergio +9 more
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Dynamics of change glioneyronal complex retinal photodamage, usingmathematical modeling methods
Бюллетень сибирской медицины, 2012 Using electron microscopy and morphometric analysis studied the structural changes of neurons and radial glia of the retina of white mongrel male rats when exposed to light (6000 lux) in the dynamics after 1, 7, 14 and 30 days.
Ye. Yu. Varakuta +6 more
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Frontiers in Cellular Neuroscience, 2023 Photoreceptors possess a highly specialized primary cilium containing expanded ciliary membrane discs called the outer segment. The photoreceptor cilium is essential for the maintenance of the outer segment, and pathogenic variants in more than 50 cilia ...
Kei Takahashi +4 more
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