Results 21 to 30 of about 5,017 (139)
Zika Infection Disrupts Proteins Involved in the Neurosensory System
Frontiers in Cell and Developmental Biology, 2020 Newly re-emerging viruses are of great global concern, especially when there are no therapeutic interventions available during the time of an outbreak.
Kathleen K. M. Glover +11 more
doaj +1 more source
Tracking the Transplanted Neurosphere in Retinal Pigment Epithelium Degeneration Model
Basic and Clinical Neuroscience, 2021 Introduction: Retinal Pigment Epithelium (RPE) layer deterioration is a leading cause of Age-Related Macular Degeneration (AMD), i.e., the most significant reason for irreversible blindness.
Hamid Aboutaleb Kadkhodaeian +3 more
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Effects of hydroquinone on retinal and vascular cells in vitro
Indian Journal of Ophthalmology, 2012 Aim: To explore the molecular pathophysiology that might explain the epidemiologic association between cigarette smoke and age-related macular degeneration (AMD) by examining the effects of hydroquinone (HQ), a toxic compound present in high ...
Ashish Sharma +5 more
doaj +1 more source
Journal of Immunology Research, 2014 Age-related macular degeneration (AMD) is the most common cause of blindness among the elderly, especially in Western countries. Although the prevalence, risk factors, and clinical course of the disease are well described, its pathogenesis is not ...
Milosz P. Kawa +3 more
doaj +1 more source
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Radial outer retina reflectivity (RORR) sign in LAMP2‐associated retinopathy
Acta Ophthalmologica, EarlyView.Abstract Purpose To describe the radial outer retina reflectivity (RORR) sign in patients carrying pathogenic variants in the X‐linked lysosome‐associated membrane protein‐2 (LAMP2) gene and to review the histologic characteristics of LAMP2 expression in the human retina.
Rachael C. Heath Jeffery +17 more
wiley +1 more source
Retinal Neurodegeneration in db/db Mice at the Early Period of Diabetes
Journal of Ophthalmology, 2015 Purpose. To describe both the functional and pathological alternations in neurosensory retina in a murine model of spontaneous type 2 diabetes (db/db mouse). Methods. db/db (BKS/DB−/−) mice and heterozygous littermates (as control group) at various ages (
Qin Yang +7 more
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Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Background Retinopathy of prematurity (ROP) is a neurovascular disorder that may affect not only the retina but also the brain structures involved in visual processing. The relationship between ROP severity and the volumetric development of these regions remains unclear.
Jose Uberos +8 more
wiley +1 more source
Optical Coherence Tomography in Inherited Macular Dystrophies: A Review
DiagnosticsMacular dystrophies (MDs) constitute a collection of hereditary retina disorders leading to notable visual impairment, primarily due to progressive macular atrophy.
Alba Gómez-Benlloch +8 more
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Scientific Reports, 2021 Retinal pigment epithelial (RPE) cells that underlie the neurosensory retina are essential for the maintenance of photoreceptor cells and hence vision. Interactions between the RPE and their basement membrane, i.e.
Rawshan Choudhury +10 more
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