Results 1 to 10 of about 129,811 (264)

Pulmonary endothelial cells from different vascular segments exhibit unique recovery from acidification and Na+/H+ exchanger isoform expression

PLoS ONE, 2022
Sodium-hydrogen exchangers (NHEs) tightly regulate intracellular pH (pHi), proliferation, migration and cell volume. Heterogeneity exists between pulmonary endothelial cells derived from different vascular segments, yet the activity and isoform ...
Dylan Adams, Chung-Sik Choi, Sarah L. Sayner   +2 more
doaj   +2 more sources

Influenza A virus infects pulmonary microvascular endothelial cells leading to microvascular leakage and release of pro-inflammatory cytokines [PDF]

PeerJ, 2021
Objective To investigate the replication of influenza A virus A/Puerto Rico/8/34 (H1N1) in pulmonary microvascular endothelial cells and its effect on endothelial barrier function.
Tiantian Han, Yanni Lai, Yong Jiang, Xiaohong Liu, Danhua Li   +4 more
doaj   +2 more sources

Integrin binding peptides facilitate growth and interconnected vascular-like network formation of rat primary cortical vascular endothelial cells in vitro

Neural Regeneration Research, 2023
Neovascularization and angiogenesis in the brain are important physiological processes for normal brain development and repair/regeneration following insults.
Ram Kuwar, Xuejun Wen, Ning Zhang, Dong Sun   +3 more
doaj   +1 more source

Lactate dehydrogenase a expression is necessary to sustain rapid angiogenesis of pulmonary microvascular endothelium. [PDF]

PLoS ONE, 2013
Angiogenesis is a fundamental property of endothelium, yet not all endothelial cells display equivalent angiogenic responses; pulmonary microvascular endothelial cells undergo rapid angiogenesis when compared to endothelial cells isolated from conduit ...
Glenda Parra-Bonilla, Diego F Alvarez, Mikhail Alexeyev, Audrey Vasauskas, Troy Stevens   +4 more
doaj   +1 more source

Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy

Nature Communications, 2023
Vascular mechanisms of Alzheimer’s disease (AD) may constitute a therapeutically addressable biological pathway underlying dementia. We previously demonstrated that soluble pathogenic forms of tau (tau oligomers) accumulate in brain microvasculature of ...
Stacy A. Hussong, Andy Q. Banh, Candice E. Van Skike, Angela O. Dorigatti, Stephen F. Hernandez, Matthew J. Hart, Beatriz Ferran, Haneen Makhlouf, Maria Gaczynska, Pawel A. Osmulski, Salome A. McAllen, Kelly T. Dineley, Zoltan Ungvari, Viviana I. Perez, Rakez Kayed, Veronica Galvan   +15 more
doaj   +1 more source

Immunomagnetic Isolation and Enrichment of Microvascular Endothelial Cells from Human Adipose Tissue

Bio-Protocol, 2022
Human adipose tissue-resident microvascular endothelial cells are not only garnering attention for their emergent role in the pathogenesis of obesity-related metabolic disorders, but are also of considerable interest for vascular tissue engineering due ...
Jeremy Antonyshyn, Vienna Mazzoli, Meghan McFadden, Anthony Gramolini, Stefan Hofer, Craig Simmons, J. Paul Santerre   +6 more
doaj   +1 more source

Targeting brain microvascular endothelial cells: a therapeutic approach to neuroprotection against stroke

Neural Regeneration Research, 2015
Brain microvascular endothelial cells form the interface between nervous tissue and circulating blood, and regulate central nervous system homeostasis. Brain microvascular endothelial cells differ from peripheral endothelial cells with regards expression
Qi-jin Yu, Hong Tao, Xin Wang, Ming-chang Li   +3 more
doaj   +1 more source

Identification of Cell-Surface Proteins Endocytosed by Human Brain Microvascular Endothelial Cells In Vitro

Pharmaceutics, 2020
Cell-surface proteins that can endocytose into brain microvascular endothelial cells serve as promising candidates for receptor-mediated transcytosis across the blood–brain barrier (BBB).
Shingo Ito, Mariko Oishi, Seiryo Ogata, Tatsuki Uemura, Pierre-Olivier Couraud, Takeshi Masuda, Sumio Ohtsuki   +6 more
doaj   +1 more source

Induction of brain microvascular endothelial cell urokinase expression by Cryptococcus neoformans facilitates blood-brain barrier invasion. [PDF]

PLoS ONE, 2012
The invasive ability of the blood-borne fungal pathogen Cryptococcus neoformans can be enhanced through interactions with host plasma components, such as plasminogen.
Jamal Stie, Deborah Fox
doaj   +1 more source

Robo4 inhibits gamma radiation-induced permeability of a murine microvascular endothelial cell by regulating the junctions

Cellular & Molecular Biology Letters, 2023
Background Hematopoietic stem cell transplantation involves irradiation preconditioning which causes bone marrow endothelial cell dysfunction. While much emphasis is on the reconstitution of hematopoietic stem cells in the bone marrow microenvironment ...
Seyram Yao Adzraku, Guozhang Wang, Can Cao, Yurong Bao, Yizhou Wang, Alhaji Osman Smith, Yuwei Du, Haiyang Wang, Yue Li, Kailin Xu, Jianlin Qiao, Wen Ju, Lingyu Zeng   +12 more
doaj   +1 more source