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Targeting brain microvascular endothelial cells: a therapeutic approach to neuroprotection against stroke

open access: yesNeural Regeneration Research, 2015
Brain microvascular endothelial cells form the interface between nervous tissue and circulating blood, and regulate central nervous system homeostasis. Brain microvascular endothelial cells differ from peripheral endothelial cells with regards expression
Qi-jin Yu   +3 more
doaj   +3 more sources

Isolation of Microvascular Endothelial Cells

open access: yesBio-Protocol, 2018
The vascular endothelium is essential to normal vascular homeostasis. Its dysfunction participates in various cardiovascular disorders. Murine endothelial cell culture is an important tool for cardiovascular disease research. This protocol demonstrates a
Kenneth Cheung, Federica Marelli-Berg
doaj   +4 more sources

Microvascular endothelial cells of the corpus luteum [PDF]

open access: yesReproductive Biology and Endocrinology, 2003
The cyclic nature of the capillary bed in the corpus luteum offers a unique experimental model to examine the life cycle of endothelial cells, involving discrete physiologically regulated steps of angiogenesis, blood vessel maturation and blood vessel ...
Spanel-Borowski Katherina   +2 more
doaj   +3 more sources

Human Liver Endothelial Cells, But Not Macrovascular or Microvascular Endothelial Cells, Engraft in the Mouse Liver [PDF]

open access: yesCell Transplantation, 2013
Liver cell transplantation has had limited clinical success so far, partly due to poor engraftment of hepatocytes. Instead of hepatocytes. other cell types, such as endothelial cells, could be used in ex vivo liver gene therapy.
Ebtisam El Filali   +4 more
doaj   +4 more sources

Pulmonary endothelial cells from different vascular segments exhibit unique recovery from acidification and Na+/H+ exchanger isoform expression

open access: yesPLoS ONE, 2022
Sodium-hydrogen exchangers (NHEs) tightly regulate intracellular pH (pHi), proliferation, migration and cell volume. Heterogeneity exists between pulmonary endothelial cells derived from different vascular segments, yet the activity and isoform ...
Dylan Adams   +2 more
doaj   +2 more sources

Influenza A virus infects pulmonary microvascular endothelial cells leading to microvascular leakage and release of pro-inflammatory cytokines [PDF]

open access: yesPeerJ, 2021
Objective To investigate the replication of influenza A virus A/Puerto Rico/8/34 (H1N1) in pulmonary microvascular endothelial cells and its effect on endothelial barrier function.
Tiantian Han   +4 more
doaj   +2 more sources

Integrin binding peptides facilitate growth and interconnected vascular-like network formation of rat primary cortical vascular endothelial cells in vitro

open access: yesNeural Regeneration Research, 2023
Neovascularization and angiogenesis in the brain are important physiological processes for normal brain development and repair/regeneration following insults.
Ram Kuwar   +3 more
doaj   +1 more source

Lactate dehydrogenase a expression is necessary to sustain rapid angiogenesis of pulmonary microvascular endothelium. [PDF]

open access: yesPLoS ONE, 2013
Angiogenesis is a fundamental property of endothelium, yet not all endothelial cells display equivalent angiogenic responses; pulmonary microvascular endothelial cells undergo rapid angiogenesis when compared to endothelial cells isolated from conduit ...
Glenda Parra-Bonilla   +4 more
doaj   +1 more source

Retroviral transformation of cerebral microvascular endothelial cells: macrophage-like and microvascular endothelial cell properties [PDF]

open access: yesBlood, 1991
We report that L-cell-conditioned medium (LCM) transforms porcine cerebral microvascular (PCMV) endothelial cells into cells with macrophage-like properties. LCM is known to contain both cytokine(s) and the L-cell virus, a murine retrovirus found in the L929 cell and LCM. Our evidence suggests that both LCM cytokine(s) and the L-cell virus are involved
D H, Robinson   +5 more
openaire   +3 more sources

Cell Chirality of Micropatterned Endometrial Microvascular Endothelial Cells

open access: yesAdvanced Healthcare Materials, 2023
ABSTRACT Chirality is an intrinsic cellular property that describes cell polarization biases along the left-right axis, apicobasal axis, or front-rear axes. Cell chirality plays a significant role in the arrangement of organs in the body as well as the orientation of organelles, cytoskeletons, and cells.
Samantha G. Zambuto   +4 more
openaire   +3 more sources

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