Results 21 to 30 of about 123,827 (263)

Anti-endothelial cell antibodies in pathogenesis of vasculitis

Frontiers in Immunology
Vasculitis is a group of syndromes characterized by inflammation, presence of autoantibodies and endothelial cells (ECs) damage, which lead to stenosis or occlusion of the vascular lumen. Anti-endothelial cell antibodies (AECAs) are a heterogeneous group
Tian Zhang, Tian Zhang, Tian Zhang, Liqun Li, Shengshi Huang, Shengshi Huang, Shengshi Huang, Maria N. Starodubtseva, Maria N. Starodubtseva, Ju Liu, Ju Liu, Ju Liu   +11 more
doaj   +1 more source

Microvascular Endothelial Cell Culture.

Journal of Investigative Dermatology, 1989
Microvascular endothelial cells play a central role in inflammation, tumor metastasis, and wound healing. Methods to study these processes in vitro using cells isolated from adult skin, from the inner and the outer segments of the neontal foreskin, and from experimental animals are reviewed.
openaire   +2 more sources

Japanese encephalitis virus-associated human microglia induce cell death of human microvascular endothelial cells in receptor-independent infection

Frontiers in Cellular and Infection Microbiology
IntroductionThe neurotropic virus Japanese encephalitis virus invades the human central nervous system, inducing neuroinflammation and further disruption of the blood-brain barrier.
Isabelle Fellay, Pauline Blanc, Alexey Larionov, Léa Schlunke, Léa Schlunke, Luis Filgueira, Nils Lannes   +6 more
doaj   +1 more source

Mechanistic Pathogenesis of Endothelial Dysfunction in Diabetic Nephropathy and Retinopathy

Frontiers in Endocrinology, 2022
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of diabetes. Microvascular endothelial cells are thought to be the major targets of hyperglycemic injury.
Jing Yang, Jing Yang, Jing Yang, Jing Yang, Zhangsuo Liu, Zhangsuo Liu, Zhangsuo Liu, Zhangsuo Liu   +7 more
doaj   +1 more source

Effects of Fullerenols on Mouse Brain Microvascular Endothelial Cells [PDF]

International Journal of Molecular Sciences, 2017
Fullerenols, water-soluble C60-fullerene derivatives, have been shown to exert neuroprotective effects in vitro and in vivo, most likely due to their capability to scavenge free radicals. However, little is known about the effects of fullerenols on the blood–brain barrier (BBB), especially on cerebral endothelial cells under inflammatory conditions ...
Schuhmann, Michael K., Fluri, Felix
openaire   +3 more sources

Post-acute ischemic stroke hyperglycemia aggravates destruction of the blood-brain barrier

Neural Regeneration Research
[INLINE:1] Post-acute ischemic stroke hyperglycemia increases the risk of hemorrhagic transformation, which is associated with blood-brain barrier disruption.
Tianqi Xu, Jianhong Yang, Yao Xu, Xiaofeng Wang, Xiang Gao, Jie Sun, Chenhui Zhou, Yi Huang   +7 more
doaj   +1 more source

The Influence of Capsaicin on the Integrity of Microvascular Endothelial Cell Monolayers [PDF]

International Journal of Molecular Sciences, 2018
Microvascular endothelial cells are an essential part of many biological barriers, such as the blood–brain barrier (BBB) and the endothelium of the arteries and veins. A reversible opening strategy to increase the permeability of drugs across the BBB could lead to improved therapies due to enhanced drug bioavailability.
Mathias Kaiser, Malgorzata Burek, Stefan Britz, Frauke Lankamp, Steffi Ketelhut, Björn Kemper, Carola Förster, Christian Gorzelanny, Francisco M. Goycoolea   +8 more
openaire   +4 more sources

Effect of glucocorticoids on lncRNA and mRNA expression profiles of the bone microcirculatory endothelial cells from femur head of Homo sapiens

Genomics Data, 2015
Appropriate gene expression patterns form the basis for bone microvascular endothelial cells' function in femoral head. Although previous studies have elucidated the impact of glucocorticoids on these cells' specific gene expression the exact ...
Qingsheng Yu, Wanshou Guo, Jianying Shen, Yuming Lv   +3 more
doaj   +1 more source

Efficient co-isolation of microvascular endothelial cells and satellite cell-derived myoblasts from human skeletal muscle

Frontiers in Bioengineering and Biotechnology, 2022
Vascularization of tissue-engineered constructs remains a key challenge in the field of skeletal muscle tissue engineering. One strategy for vascularizing organoids is in vitro pre-vascularization, relying on de novo assembly of undifferentiated ...
Rebecca Wüst, Lisanne Terrie, Thomas Müntefering, Tobias Ruck, Lieven Thorrez   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source