Results 41 to 50 of about 5,017 (139)

Multiscale Cortical Remodeling Following Abrupt Visual Deafferentation in Rhegmatogenous Retinal Detachment: Imaging Transcriptomics and Neurotransmitter Mapping

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
RRD triggers multiscale cortical reorganization, including visual‐network atrophy, shortened intrinsic neural timescale, and altered structural covariance gradients. Integrating Mendelian randomization with AHBA and PET/SPECT biological anchoring and SHAP‐based classification highlights INT as a sensitive imaging biomarker for RRD‐related brain ...
Yu Ji, Xin Huang, Yuan‐Yuan Wang, Lin Zhou, Zhuo‐Er Dong, Xiao‐Rong Wu   +5 more
wiley   +1 more source

Assessment of photoreceptor recovery and visual function utilizing adaptive optics and microperimetry in patients with surgically closed macular holes

Photodiagnosis and Photodynamic Therapy
Background: This study investigated the association between photoreceptor structural restoration and visual function outcomes in patients undergoing surgery for closed macular holes (MHs).
Yuanyuan Liu, Xueli Yang, Wei Zhou, Jinguo Yu, Song Chen, Tiangeng He, Caiyun You, Xiangda Meng, Mengyu Liao, Yi Lei, Hua Yan   +10 more
doaj   +1 more source

Corneal arcus and xanthomas in homozygous familial hypercholesterolemia: First report from China

Indian Journal of Ophthalmology, 2013
We report the case of a 12-year-old male who developed corneal arcus and multiple skin lesions with a 10-year history of xanthomas. The lesions appeared over his fingers, hands, elbows, knees, buttocks and feet.
Xin Meng, Jie Lin, Xinxiao Gao, Jia Guo, Chen Xin, Jun Wang   +5 more
doaj   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Assessment of peripapillary retinal nerve fiber layer thickness using scanning laser polarimetry (GDx VCC) in normal Indian children

Indian Journal of Ophthalmology, 2013
Purpose: To obtain reference values of RNFL thickness in normal Indian children and to study the association of RNFL thickness with central corneal thickness(CCT) and axial length(AL). Materials and Methods: 200 normal Indian children (mean age 8.6 ± 2.9
Mayuri B Khamar, Vaishali Vasavada, Sajani K Shah, Rupal H Trivedi, Ravi Thomas   +4 more
doaj   +1 more source

Oxygen diffusion kinetics, buffering capacity and phenotype: A narrative review of oxygen physiology and later phenotype in very preterm infants

Experimental Physiology, Volume 111, Issue 5, Page 2485-2493, 1 May 2026.
Abstract Clinicians often view exposure to supplementary oxygen in preterm infants as a simple reciprocal trade‐off between mortality and the risk of vision‐threatening retinopathy, but this perspective oversimplifies the underlying physiology. Oxygen moves through a series of spatially distinct compartments without intrinsic regulation, with Fick's ...
Chad C Andersen, Danielle N Bailey, Tara M Crawford, Michael J Stark   +3 more
wiley   +1 more source

Pattern of blood vessels in eyes with coloboma

Indian Journal of Ophthalmology, 2013
Background: Choroidal coloboma, especially with optic disc involvement affects the blood vessel (BV) pattern in the fundus. Aim: The aim of this study was to report the observations on the pattern of retinal BVs in eyes with fundus coloboma.
Gopal Lingam
doaj   +1 more source

Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer’s Disease

Acta Neuropathologica Communications, 2021
Retina and optic nerve are sites of extra-cerebral manifestations of Alzheimer’s Disease (AD). Amyloid-β (Aβ) plaques and neurofibrillary tangles of hyperphosphorylated tau protein are detected in eyes from AD patients and transgenic animals in ...
Valentina Latina, Giacomo Giacovazzo, Federica Cordella, Bijorn Omar Balzamino, Alessandra Micera, Monica Varano, Cristina Marchetti, Francesca Malerba, Rita Florio, Bruno Bruni Ercole, Federico La Regina, Anna Atlante, Roberto Coccurello, Silvia Di Angelantonio, Pietro Calissano, Giuseppina Amadoro   +15 more
doaj   +1 more source

Endogenous Endophthalmitis Caused by Aspergillus lentulus in an Immunocompromised Patient with Lung Cancer

Türk Oftalmoloji Dergisi
A 78-year-old man with a history of lung cancer, chemotherapy, radiotherapy, and coronavirus disease 2019 infection experienced visual deterioration of two-weeks’ duration in his right eye.
Mustafa Kayabaşı, Ziya Ayhan, Banu Lebe, Ayşe Aydan Özkütük, Meltem Söylev Bajin, Arzu Nazlı, Eyüp Sabri Uçan, Aziz Karaoğlu, Ali Osman Saatci   +8 more
doaj   +1 more source

Clinical features and etiology of retinal vasculitis in Northern Thailand

Indian Journal of Ophthalmology, 2013
Purpose: To report on the clinical features and etiology of patients with retinal vasculitis (RV). Materials and Methods: We reviewed medical records of 47 patients (75 affected eyes) diagnosed with RV.
Supanut Apinyawasisuk, Aniki Rothova, Paradee Kunavisarut, Kessara Pathanapitoon   +3 more
doaj   +1 more source