Results 51 to 60 of about 506,489 (355)
China Geology: Xinqiao Gully is located in the area of the 2008 Wenchuan Ms 8.0 earthquake in Sichuan province, China. Based on the investigation of the 2023 “6-26” Xinqiao Gully debris flow event, this study assessed the effectiveness of the debris flow control ...
Chang Yang +5 more
doaj +1 more source
Assessment and Analysis of a Rainfall–Time-Lagging Water-Related Disaster in Mountainous Areas
Frontiers in Earth Science, 2021 Both global climate change and human activities are continuously impacting the abruptness and frequency of water-related natural disasters such as flash floods, debris flows, and landslides in mountainous areas, greatly threatening the safety of lives ...
Xu-Feng Yan +5 more
doaj +1 more source
Numerical simulation of debris flows triggered from the Strug rock fall source area, W Slovenia [PDF]
, 2006 The Strug landslide was triggered in December 2001 as a rockslide, followed by a rock fall. In 2002, about 20 debris flows were registered in the Kosec village; they were initiated in the Strug rock fall source area.
Fazarinc, Rok +7 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Zhongguo dizhi zaihai yu fangzhi xuebao, 2022 Post-fire debris flow is a special torrent containing a large amount of loose material, which is closely related to forest fire. Its characteristics are significantly different from the conventional debris flow.
Xiangbin YANG +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Experimental study on the impact of wide graded debris flow on check dam in high altitude area
Shuiwen dizhi gongcheng dizhiThe impact force of debris flow is the main cause of damage and destruction of check dam. In high altitude area, due to high mountains and deep valleys, serious physical weathering of surface materials, a wide range of source materials gradation, high ...
Shengqing HE, Da ZHENG, Wen ZHANG
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
An Assessment Method for Debris Flow Dam Formation in Taiwan
Earth Sciences Research Journal, 2018 Debris flows in tributaries rush into and block the main branches of rivers and often result in serious hazards. Dam failures cause large floods in the downstream area and can lead to fatalities and property damage.
Kun-Ting Chen +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source