Results 61 to 70 of about 494,604 (306)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Lattice-Boltzmann Method for Geophysical Plastic Flows
, 2015 We explore possible applications of the Lattice-Boltzmann Method for the simulation of geophysical flows. This fluid solver, while successful in other fields, is still rarely used for geotechnical applications.
C. Ancey +19 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Simulasi Penanganan Potensi Aliran Debris di Gunung Sago (Studi Kasus di Batang Lakin, Kecamatan Lareh Sago Halaban, Kabupaten Lima Puluh Kota) [PDF]
, 2014 The regions in foothills of Sago mountain are flood-prone area due to debris flow. As occurred on March 22, 2010, there has been a catastrophic overflow of debris flow from Sago mountain.
Hadthya, R. \u27. (Reinhart) +2 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Experimental study on the impact load characteristics of a single-row pile dam against debris flow
Geomatics, Natural Hazards & RiskA single-row pile dam is a type of rigid debris flow barrier structure. In order to reveal the mutual interaction effects between debris flow and a single-row pile dam and the distribution law of debris flow impact forces, an analysis of the correlation ...
Hao Sun +5 more
doaj +1 more source
RRS Charles Darwin Cruise 126, 11 Mar-20 Mar 2001. Piston coring of debris flows and turbidites west and south of the Canary Islands [PDF]
, 2002 The major cruise objective was to obtain sediment cores at various locations to the west and southwest of the Canary Islands with the aims of :· Sampling debris flow sediments in the Canary and Saharan debris flows· Obtaining dateable sediments ...
Masson, D.G.
core
Origin and significance of 'dispersed facies' basal ice: Svínafellsjökull, Iceland [PDF]
, 2010 Dispersed facies basal ice - massive (i.e. structureless) ice with dispersed debris aggregates - is present at the margins of many glaciers and, as a product of internal glacial processes, has the potential to provide important information about the ...
Darrel A. Swift +10 more
core +3 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source