Results 51 to 60 of about 6,888 (239)

The role of sulfidation of Fe-carbonate rocks in increasing gold contents at the Zarshuran deposit (northern Takab), Takab-Angouran metallogenic district

Journal of Economic Geology, 2022
Iron and arsenic sulfides are considered as the most important gold hosts in the sediment-hosted disseminated invisible gold deposits. The Zarshuran gold deposit (155 tons Au with average grade of 2.63 g/t) is formed in the Lower Cambrian black shale and
Sharareh Heshmatnia, Ebrahim Tale Fazel, Abbas Oroji   +2 more
doaj   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Optimized Methyl methacrylate embedding of small and large undecalcified bones.

MethodsX
Methyl methacrylate (MMA) plastic embedding has been long established as a technique for the processing and histological assessment of bones. It provides the added benefit over paraffin in that it does not require decalcification of the tissue in order ...
Jackie A. Fretz, Nancy W. Troiano
doaj   +1 more source

Three-dimensional hard and soft tissue imaging of the human cochlea by scanning laser optical tomography (SLOT).

PLoS ONE, 2017
The present study focuses on the application of scanning laser optical tomography (SLOT) for visualization of anatomical structures inside the human cochlea ex vivo. SLOT is a laser-based highly efficient microscopy technique which allows for tomographic
Nadine Tinne, Georgios C Antonopoulos, Saleh Mohebbi, José Andrade, Lena Nolte, Heiko Meyer, Alexander Heisterkamp, Omid Majdani, Tammo Ripken   +8 more
doaj   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

Development of patient-tailored preoperative assessment of percutaneous vertebroplasty

Frontiers in Surgery
Percutaneous vertebroplasty (PVP), a minimally invasive surgery technique, has become the common treatment for osteoporotic vertebral compression fractures (OVCF).
Yian Lu, Qunhua Jiang
doaj   +1 more source

Bamboo‐Like Whiskers‐Reinforced Bioceramics Accelerate Large Segmental Bone Regeneration via Dual Modulation of Type‐H Vessels and Osteoinduction

Advanced Science, EarlyView.
The graphical abstract image of bamboo‐like whisker‐reinforced Ca‐P bioceramics accelerating large segmental bone regeneration. ABSTRACT Regenerative repair of segmental bone defect remains a major clinical challenge. The conventional mental implants suffer from mechanical strength mismatch and long‐term foreign bodies presence.
Cong Feng, Haibo Teng, Chuyao Xu, Jiaze He, Keting Liu, Xueying Li, Kai Zhang, Xiangdong Zhu, Xiangfeng Li, Jianguo Xu, Xingdong Zhang   +10 more
wiley   +1 more source

Amorphous calcium phosphate nanoparticles-based mouthwash: preparation, characterization, and anti-bacterial effects

Green Chemistry Letters and Reviews, 2019
The objective of this study is to prepare a novel mouthwash that contains Amorphous Calcium Phosphate nanoparticles (ACP-NPs) in a chitosan aqueous solution in order to prevent and treat the existing enamel decalcification around the brackets and ...
Kimiya Pakravanan, Mahmood Rezaee Roknabadi, Fahimeh Farzanegan, Alireza Hashemzadeh, Majid Darroudi   +4 more
doaj   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

Advanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang, Xiuying Jiang, Xi Sun, Hao Chen, Jianjun Jin, Xin'e Shi   +5 more
wiley   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

Advanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li, Xin Xing, Beicheng Du, Myles Zhou, Austin Z. Chen, Mary Archer, Chunbao Rao, Manyu Zhu, Masnsen Cherief, Aaron W. James   +9 more
wiley   +1 more source