Results 241 to 250 of about 81,314 (317)

Pyridoxal 5'-Phosphate-Dependent Enzymatic Decarboxylative Annulation. [PDF]

J Am Chem Soc
Chai W, Luo S, Xi W, He X, Zhang T, Zou Y, Hai Y.   +6 more
europepmc   +1 more source

Phenotypic characterization of Arabidopsis thaliana mutants that alleviate root growth defects in a vitamin B6 biosynthesis mutant

The FEBS Journal, EarlyView.
Vitamin B6 is a critical molecule for plant metabolism and development. Rsr4‐1, a loss‐of‐function mutant in a vitamin B6 biosynthesis gene, has a distinct short root phenotype. Here we describe five novel suppressor mutants with an rsr4‐1 background that have normalized root growth and distinct phenotypic and molecular characteristics, representing a ...
Marcelina Parra, Paige Henning, Clayton Bailes, Sanja Roje, Hanjo Hellmann   +4 more
wiley   +1 more source

Transient Salt-Bridge-Based Supramolecular Polymers: Experiments and Theory. [PDF]

J Am Chem Soc
Melchiorre G, Valentini M, Ranieri F, Cantiello D, Cacciapaglia R, Baldini L, Ercolani G, Di Stefano S.   +7 more
europepmc   +1 more source

Common pathways and outliers in glucose catabolism across Trypanosomatidae

The FEBS Journal, EarlyView.
Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes, Mayke B. Alencar, Ariel M. Silber, Ingrid Škodová‐Sveráková, Kristína Záhonová, Vyacheslav Yurchenko   +5 more
wiley   +1 more source

Substitutive Approach Toward Heteroaromatic Amino Alcohols Accessed Through Dioxolanyl Radical Linchpin. [PDF]

Adv Synth Catal
Chang JJ, Kumar M, Kashatus RC, Tomaselli DJ, Kim DK.   +4 more
europepmc   +1 more source

Structural and mutational analysis of Methanosarcina mazei prenylated FMN synthase reveals the basis of its unique prenyl donor substrate specificity

The FEBS Journal, EarlyView.
Some prenylated flavin mononucleotide (prFMN) synthases exceptionally prefer dimethylallyl phosphate (DMAP) over dimethylallyl diphosphate (DMAPP), which is a common prenyl donor substrate for many prenyltransferases. Structural and mutagenic analyses of Methanosarcina mazei prFMN synthase, which prefers DMAP but can also accept DMAPP, elucidated its ...
Sou Fukuhara, Hideaki Unno, Soma Ishimine, Ryuhei Nagata, Tomokazu Ito, Hisashi Hemmi   +5 more
wiley   +1 more source

Role of Aspartate 86 in the Catalytic Mechanism of <i>Escherichia coli</i> Glutamate Decarboxylase. [PDF]

Biochemistry
Giovannercole F, Pennacchietti E, Grassini G, De Biase D.   +3 more
europepmc   +1 more source

Methionine Regulates Antitumour Function of CD8+ T Cells Through Polyamine Synthesis

Immunology, EarlyView.
Methionine restriction in vitro enhances CD8+ T cell effector function by suppressing polyamine synthesis and progressively induces the co‐expression of PD‐1 and TIM‐3. Consistently, sustained dietary methionine restriction diminishes the efficacy of adoptive T cell therapy (ACT) and promotes the expression of terminal exhaustion‐associated markers ...
Tian Zhao, Gillian A. Carleton, Sam Preshaw, Sarah MacPherson, Madison Shiyuk, Joseph Monaghan, Jun Han, Oro Uchenunu, Robert Rottapel, Ralph J. DeBerardinis, Kelly M. Stewart, Bo‐Hyun Kim, Juan Ausió, David R. Goodlett, Helena Pětrošová, Kyle D. Duncan, Julian J. Lum   +16 more
wiley   +1 more source

A generic solvothermal defluorination method for carboxylate and sulfonate PFAS. [PDF]

Chem Sci
Strijckmans N, Stuyck W, Hooyberghs F, Coppée T, Hulaj G, Lauwers A, O'Rourke G, Ameloot R, Chanut N, De Vos DE.   +9 more
europepmc   +1 more source

Cascade Iodine-Catalyzed Synthesis of Nitrogenated Aromatics from 2-Pyrones. [PDF]

J Org Chem
Souza BB, Cabral TLG, Varriano CB, Tormena CF, Pastre JC.   +4 more
europepmc   +1 more source