Results 91 to 100 of about 15,112 (276)
Innovation in ovary decellularization methods: Chemical and herbal detergents
Regenerative TherapyThe ovary provides an ideal environment for egg survival due to its distinct structure that directly contributes to the growth and maintenance of the follicle.
Mozafar Khazaei +3 more
doaj +1 more source
PLoS ONE, 2023 IntroductionLarge bone defects are challenging for surgeons. Available reimplanted bone substitutes can't properly restore optimal function along and long term osteointegration of the bone graft.
Ugo Heller +5 more
doaj +1 more source
Decellularized scaffolds in regenerative medicine
Oncotarget, 2016 Allogeneic organ transplantation remains the ultimate solution for end-stage organ failure. Yet, the clinical application is limited by the shortage of donor organs and the need for lifelong immunosuppression, highlighting the importance of developing effective therapeutic strategies.
Yu, Yaling +3 more
openaire +2 more sources
Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues
Advanced Healthcare Materials, EarlyView.Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman +7 more
wiley +1 more source
Pressure Shift Freezing as Potential Alternative for Generation of Decellularized Scaffolds
International Journal of Biomaterials, 2013 Background. Protocols using chemical reagents for scaffold decellularization can cause changes in the properties of the matrix, depending on the type of tissue and the chemical reagent.
S. Eichhorn +6 more
doaj +1 more source
Lung bioengineering: physical stimuli and stem/progenitor cell biology interplay towards biofabricating a functional organ [PDF]
, 2016 A current approach to obtain bioengineered lungs as a future alternative for transplantation is based on seeding stem cells on decellularized lung scaffolds.
Campillo, Noelia +5 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Percutaneous prosthetic venous valves are fabricated by embedding stents in an electrospun matrix that extends luminally to form leaflets. The design shields leaflets from hyperplastic cells, isolates struts from blood contact, and avoids discrete anchoring points.
Dario Arcuti +6 more
wiley +1 more source
Effect of fluid dynamics on decellularization efficacy and mechanical properties of blood vessels.
PLoS ONE, 2019 Decellularization of blood vessels is a promising approach to generate native biomaterials for replacement of diseased vessels. The decellularization process affects the mechanical properties of the vascular graft and thus can have a negative impact for ...
Robin Simsa +6 more
doaj +1 more source
Sterile acellular dermal collagen as a treatment for rippling deformity of breast. [PDF]
, 2014 Prosthetic implants are frequently used for breast augmentation and breast reconstruction following mastectomy. Unfortunately, long-term aesthetic results of prosthetic breast restoration may be hindered by complications such as rippling, capsular ...
Busse, Brittany +2 more
core +3 more sources
Advanced Materials, EarlyView.An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang +5 more
wiley +1 more source