Contribution of physical methods in decellularization of animal tissues
Biologic scaffolds composed of extracellular matrix (ECM) are frequently used for clinical purposes of tissue regeneration. Different methods have been developed for this purpose.
Mohsen Rabbani +2 more
doaj +1 more source
Uterine regeneration using decellularization scaffolds provides a novel treatment for uterine factor infertility. Decellularized scaffolds require maximal removal of cellular components and minimal damage to the extracellular matrix (ECM).
Dongzhe Wang +6 more
doaj +1 more source
Structural Integrity of Aortic Scaffolds Decellularized by Sonication Decellularization System [PDF]
Sonication decellularization technique has shown effectiveness to remove all the cellular components by the disruption of the cell membranes and removal of the cell debris to prepare the bioscaffolds. However, it is important to confirm whether this technique does not have a detrimental effect on elastin and collagen in bioscaffolds.
Aqilah Hazwani +2 more
openaire +1 more source
Development of equipment for decellularization using the perfusion method
This study describes the development of equipment capable of transporting decellularization fluid through an organ by perfusion to create an in vitro acellular scaffold that maintains the three-dimensional architecture of the organ.
Jonathas Haniel +5 more
doaj +1 more source
Identification of tissue sections from decellularized liver scaffolds for repopulation experiments
Background: Biological organ engineering is a novel experimental approach to generate functional liver grafts by decellularization and repopulation. Currently, healthy organs of small or large animals and human organs with preexisting liver diseases are ...
Philipp Felgendreff +6 more
doaj +1 more source
Sterilization of lung matrices by supercritical carbon dioxide [PDF]
Lung engineering is a potential alternative to transplantation for patients with end-stage pulmonary failure. Two challenges critical to the successful development of an engineered lung developed from a decellularized scaffold include (i) the suppression
Balestrini, Jenna L +10 more
core +2 more sources
Water absorption by decellularized dermis [PDF]
Water absorption by decellularized dermis was investigated and compared with biopolymer and synthetic polymer hydrogels (glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogel, respectively). Porcine dermis was decellularized in an aqueous sodium dodecyl sulfate (SDS) solution. Histological evaluation revealed that the SDS-treated
Yongwei Zhang +7 more
openaire +3 more sources
Decellularized diaphragmatic muscle drives a constructive angiogenic response in vivo [PDF]
Skeletal muscle tissue engineering (TE) aims to efficiently repair large congenital and acquired defects. Biological acellular scaffolds are considered a good tool for TE, as decellularization allows structural preservation of tissue extracellular matrix
Alvar\ue8z Fallas, Mario +11 more
core +4 more sources
Developing Regenerative Treatments for Developmental Defects, Injuries, and Diseases Using Extracellular Matrix Collagen-Targeting Peptides. [PDF]
Collagen is the most widespread extracellular matrix (ECM) protein in the body and is important in maintaining the functionality of organs and tissues.
Goldbloom-Helzner, Leora +2 more
core +1 more source
Effect of pulsatile flow perfusion on decellularization
Background Decellularized animal organs have been used as scaffolds for tissue engineering. To make a properly functioning scaffolds, the extracellular matrix (ECM) components must be preserved after decellularization.
Sung Min Park +3 more
doaj +1 more source

