Results 31 to 40 of about 13,537 (233)

EXPERIENCE OF PERFUSION RECELLULARIZATION OF BIOLOGICAL LUNG SCAFFOLD IN RATS

Вестник трансплантологии и искусственных органов, 2016
Aim. The main aim of our research is to evaluate the process of rat lung decellularization and recellularization as the initial step of tissue-engineered organs creation.Materials and methods.
E. V. Kuevda, E. A. Gubareva, A. S. Sotnichenko, I. S. Gumenyuk, I. V. Gilevich, I. S. Polyakov, V. A. Porhanov, S. N. Alekseenko, P. Macchiarini   +8 more
doaj   +1 more source

A typical method for decellularization of plants as biomaterials

MethodsX, 2023
Decellularization is a process by which cells are removed from tissues or organs, leaving behind the extracellular matrix (ECM) structure. This process has gained interest in the fields of tissue engineering and regenerative medicine as a way to prepare ...
Melis Toker-Bayraktar, Melek İpek Ertugrul, Sedat Odabas, Bora Garipcan   +3 more
doaj   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source

Decellularization of Trachea With Combined Techniques for Tissue-Engineered Trachea Transplantation [PDF]

Clinical and Experimental Otorhinolaryngology, 2019
Objectives The purpose of this study is to shorten the decellularization time of trachea by using combination of physical, chemical, and enzymatic techniques.
Aysegul Batioglu-Karaaltin, Ercüment Ovali, Mehmet V Karaaltin, Murat Yener, Mehmet Yılmaz, Fatma Eyüpoğlu, Yetkin Zeki Yılmaz, Erol Rüştü Bozkurt, Necdet Demir, Esma Konuk, Ergun Süreyya Bozdağ, Özgür Yiğit, Harun Cansiz   +12 more
doaj   +1 more source

Efficient Decellularization of the Full-Thickness Rat-Derived Abdominal Wall to Produce Acellular Biologic Scaffolds for Tissue Reconstruction: Promising Evidence Acquired from In Vitro Results

Bioengineering, 2023
Background: Functional restoration of abdominal wall defects represents one of the fundamental challenges of reconstructive surgery. Synthetic grafts or crosslinked animal-derived biological grafts are characterized by significant adverse reactions ...
George Skepastianos, Panagiotis Mallis, Epameinondas Kostopoulos, Efstathios Michalopoulos, Vasileios Skepastianos, Chrysoula Palazi, Lucia Pannuto, Gerasimos Tsourouflis   +7 more
doaj   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Chemical, Physical, and Biological Corneal Decellularization Methods: A Review of Literature

Journal of Ophthalmology
The cornea is one of the most commonly transplanted tissues worldwide. It is used to restore vision when severe visual impairment or blindness occurs in patients with corneal diseases or after trauma.
Alexandra Procházková, Martina Poláchová, Jakub Dítě, Magdaléna Netuková, Pavel Studený   +4 more
doaj   +1 more source

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

Advanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel, Lucia L. Nash, Abigail J. Clevenger, Claudia A. Collier, Oscar R. Benavides, Sanjana Roy, Brinlee Goggans, Aelita Salikhova, Anvitha Tharakesh, Svasti Haricharan, Amber N. Stratman, Scott Kopetz, Alex J. Walsh, Shreya A. Raghavan   +13 more
wiley   +1 more source

Optimization of Complete Rat Heart Decellularization Using Artificial Neural Networks

Micromachines, 2022
Whole organ decellularization techniques have facilitated the fabrication of extracellular matrices (ECMs) for engineering new organs. Unfortunately, there is no objective gold standard evaluation of the scaffold without applying a destructive method ...
Greta Ionela Barbulescu, Taddeus Paul Buica, Iacob Daniel Goje, Florina Maria Bojin, Valentin Laurentiu Ordodi, Gheorghe Emilian Olteanu, Rodica Elena Heredea, Virgil Paunescu   +7 more
doaj   +1 more source

Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss

Advanced Healthcare Materials, EarlyView.
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan, Gaoxian Chen, Ishita Jain, Sha Chen, Gladys Chiang, Caroline Hu, Renato Reyes, Beu P. Oropeza, Ngan F. Huang   +8 more
wiley   +1 more source