Decellularization of pericardial tissue and its impact on tensile viscoelasticity and glycosaminoglycan content [PDF]
, 2011 Bovine pericardium is a collagenous tissue commonly used as a natural biomaterial in the fabrication of cardiovascular devices. For tissue engineering purposes, this xenogeneic biomaterial must be decellularized to remove cellular antigens.
Allen +45 more
core +2 more sources
Optimized protocol for whole organ decellularization
European Journal of Medical Research, 2017 Background The idea of tissue decellularization to gain matrices for tissue engineering is promising. The aim of the present study is to establish a safe and reproducible protocol for solid tissue decellularization that prevents the architecture of the ...
A. Schmitt +8 more
doaj +1 more source
A perfusion decellularization heart model - an interesting tool for cell-matrix interaction studies
Journal of Mind and Medical Sciences, 2019 Objective. In this paper, we present a technique for whole human, pig, or rat heart decellularization in order to obtain a tool for cell-matrix interaction studies and to obtain the extracellular matrix scaffold with applications to the study of cardiac ...
Mihai Meșină +4 more
doaj +1 more source
Development of decellularization protocol for caprine small intestine submucosa as a biomaterial
Biomaterials and Biosystems, 2022 Decellularized animal tissues have been proven to be promising biomaterials for various tissue engineering (TE) applications. Among various animal tissues, small intestine submucosa (SIS) has gained attention of many researchers due to its easy ...
Hemant Singh +5 more
doaj +1 more source
A comparison of three methods of decellularization of pig corneas to reduce immunogenicity. [PDF]
, 2014 AIM: To investigate whether decellularization using different techniques can reduce immunogenicity of the cornea, and to explore the decellularized cornea as a scaffold for cultured corneal endothelial cells (CECs).
Cooper, David KC +4 more
core +1 more source
Regeneration and Experimental Orthotopic Transplantation of a Bioengineered Kidney [PDF]
, 2014 Over 100,000 individuals in the United States currently await kidney transplantation, while 400,000 individuals live with end-stage kidney disease requiring hemodialysis. The creation of a transplantable graft to permanently replace kidney function would
Gilpin, Sarah +5 more
core +1 more source
The journey of decellularized vessel: from laboratory to operating room
Frontiers in Bioengineering and BiotechnologyOver the past few decades, there has been a remarkable advancement in the field of transplantation. But the shortage of donors is still an urgent problem that requires immediate attention.
Chenbin Kang, Hongji Yang, Hongji Yang
doaj +1 more source
Morphological evaluation of the quality of decellularized esophagus in rat
Вестник трансплантологии и искусственных органов, 2017 The main aim of our investigation was analysis and optimization of the existing protocols of esophagus decellularization in rats, identification of parameters affecting the quality of decellularization and intactness of the native properties of ...
R. Z. Nakokhov +7 more
doaj +1 more source
Tissue engineering by decellularization and 3D bioprinting [PDF]
, 2017 Discarded human donor organs have been shown to provide decellularized extracellular matrix (dECM) scaffolds suitable for organ engineering. The quest for appropriate cell sources to satisfy the need of multiple cells types in order to fully repopulate ...
Campistol Plana, Josep M. +8 more
core +1 more source
Decellularized bone extracellular matrix as a promising natural substrate for bone tissue engineering [PDF]
Exploration of BioMat-XAim: The decellularization process aims to remove cellular components from the tissues while preserving the ultrastructural composition of the extracellular matrix (ECM).
Aylin Kara Özenler +2 more
doaj +1 more source