Sterilization of lung matrices by supercritical carbon dioxide [PDF]
, 2016 Lung engineering is a potential alternative to transplantation for patients with end-stage pulmonary failure. Two challenges critical to the successful development of an engineered lung developed from a decellularized scaffold include (i) the suppression
Balestrini, Jenna L +10 more
core +2 more sources
Impact of Porcine Pancreas Decellularization Conditions on the Quality of Obtained dECM
International Journal of Molecular Sciences, 2021 Due to the limited number of organ donors, 3D printing of organs is a promising technique. Tissue engineering is increasingly using xenogeneic material for this purpose.
M. Klak +10 more
semanticscholar +1 more source
Bioengineering, 2023 Uterine regeneration using decellularization scaffolds provides a novel treatment for uterine factor infertility. Decellularized scaffolds require maximal removal of cellular components and minimal damage to the extracellular matrix (ECM).
Dongzhe Wang +6 more
doaj +1 more source
Decellularized diaphragmatic muscle drives a constructive angiogenic response in vivo [PDF]
, 2018 Skeletal muscle tissue engineering (TE) aims to efficiently repair large congenital and acquired defects. Biological acellular scaffolds are considered a good tool for TE, as decellularization allows structural preservation of tissue extracellular matrix
Alvar\ue8z Fallas, Mario +11 more
core +4 more sources
Decellularization Strategies for Regenerative Medicine: From Processing Techniques to Applications
BioMed Research International, 2017 As the gap between donors and patients in need of an organ transplant continues to widen, research in regenerative medicine seeks to provide alternative strategies for treatment.
A. Gilpin, Yong Yang
semanticscholar +1 more source
Developing Regenerative Treatments for Developmental Defects, Injuries, and Diseases Using Extracellular Matrix Collagen-Targeting Peptides. [PDF]
, 2019 Collagen is the most widespread extracellular matrix (ECM) protein in the body and is important in maintaining the functionality of organs and tissues.
Goldbloom-Helzner, Leora +2 more
core +1 more source
International Journal of Molecular Sciences, 2021 In critical nerve gap repair, decellularized nerve allografts are considered a promising tissue engineering strategy that can provide superior regeneration results compared to nerve conduits.
Marwa El Soury +6 more
semanticscholar +1 more source
Effect of pulsatile flow perfusion on decellularization
BioMedical Engineering OnLine, 2018 Background Decellularized animal organs have been used as scaffolds for tissue engineering. To make a properly functioning scaffolds, the extracellular matrix (ECM) components must be preserved after decellularization.
Sung Min Park +3 more
doaj +1 more source
Decellularization of pericardial tissue and its impact on tensile viscoelasticity and glycosaminoglycan content [PDF]
, 2011 Bovine pericardium is a collagenous tissue commonly used as a natural biomaterial in the fabrication of cardiovascular devices. For tissue engineering purposes, this xenogeneic biomaterial must be decellularized to remove cellular antigens.
Allen +45 more
core +2 more sources
The impact of decellularization methods on extracellular matrix derived hydrogels
Scientific Reports, 2019 Tissue-derived decellularized biomaterials are ideal for tissue engineering applications as they mimic the biochemical composition of the native tissue. These materials can be used as hydrogels for cell encapsulation and delivery.
Julia Fernández-Pérez, M. Ahearne
semanticscholar +1 more source