Results 51 to 60 of about 30,040 (330)

Decellularization protocol‐dependent damage‐associated molecular patterns in rat uterus scaffolds differentially affect the immune response after transplantation

open access: yesJournal of Tissue Engineering and Regenerative Medicine, 2021
Scaffolds derived from decellularized tissue possess many advantages for bioengineering applications, including for novel infertility treatments. However, the decellularization process results in allogenic‐independent damage‐associated molecular patterns
A. M. Padma   +6 more
semanticscholar   +1 more source

Optimized protocol for whole organ decellularization

open access: yesEuropean Journal of Medical Research, 2017
Background The idea of tissue decellularization to gain matrices for tissue engineering is promising. The aim of the present study is to establish a safe and reproducible protocol for solid tissue decellularization that prevents the architecture of the ...
A. Schmitt   +8 more
doaj   +1 more source

A comparison of three methods of decellularization of pig corneas to reduce immunogenicity. [PDF]

open access: yes, 2014
AIM: To investigate whether decellularization using different techniques can reduce immunogenicity of the cornea, and to explore the decellularized cornea as a scaffold for cultured corneal endothelial cells (CECs).
Cooper, David KC   +4 more
core   +1 more source

Interindividual heterogeneity affects the outcome of human cardiac tissue decellularization

open access: yesScientific Reports, 2021
The extracellular matrix (ECM) of engineered human cardiac tissues corresponds to simplistic biomaterials that allow tissue assembly, or animal derived off-the-shelf non-cardiac specific matrices.
Miguel F. Tenreiro   +6 more
semanticscholar   +1 more source

A perfusion decellularization heart model - an interesting tool for cell-matrix interaction studies

open access: yesJournal of Mind and Medical Sciences, 2019
Objective. In this paper, we present a technique for whole human, pig, or rat heart decellularization in order to obtain a tool for cell-matrix interaction studies and to obtain the extracellular matrix scaffold with applications to the study of cardiac ...
Mihai Meșină   +4 more
doaj   +1 more source

Techniques of liver decellularization [PDF]

open access: yesThe Moldovan Medical Journal, 2018
Background: The growth of the number of people who need the liver transplant and the insufficiency of organ donors, have urged the advancement in bioengineering through the development of new therapeutic strategies which involve generation of functional ...
Mariana Jian   +4 more
doaj   +1 more source

Regeneration and Experimental Orthotopic Transplantation of a Bioengineered Kidney [PDF]

open access: yes, 2014
Over 100,000 individuals in the United States currently await kidney transplantation, while 400,000 individuals live with end-stage kidney disease requiring hemodialysis. The creation of a transplantable graft to permanently replace kidney function would
Gilpin, Sarah   +5 more
core   +1 more source

Decellularization and Their Significance for Tissue Regeneration in the Era of 3D Bioprinting

open access: yesACS Omega
Three-dimensional bioprinting is an emerging technology that has high potential application in tissue engineering and regenerative medicine. Increasing advancement and improvement in the decellularization process have led to an increase in the demand for
Mrunmayi Gadre   +3 more
semanticscholar   +1 more source

Morphological evaluation of the quality of decellularized esophagus in rat

open access: yesВестник трансплантологии и искусственных органов, 2017
The main aim of our investigation was analysis and optimization of the existing protocols of esophagus decellularization in rats, identification of parameters affecting the quality of decellularization and intactness of the native properties of ...
R. Z. Nakokhov   +7 more
doaj   +1 more source

Development of decellularization protocol for caprine small intestine submucosa as a biomaterial

open access: yesBiomaterials and Biosystems, 2022
Decellularized animal tissues have been proven to be promising biomaterials for various tissue engineering (TE) applications. Among various animal tissues, small intestine submucosa (SIS) has gained attention of many researchers due to its easy ...
Hemant Singh   +5 more
doaj   +1 more source

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