NLRP7 contributes to in vitro decidualization of endometrial stromal cells
Reproductive Biology and Endocrinology, 2017 Background Nucleotide-binding oligomerization domain (NACHT), leucine rich repeat (LRR) and pyrin domain (PYD) 7 containing protein, NLRP7, is a member of the NLR family which serves as innate immune sensors.
Jyun-Yuan Huang +3 more
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Molecular Reproduction and Development, Volume 93, Issue 5, May 2026.ABSTRACT Early pregnancy loss (EPL) is a common complication with incompletely understood pathogenesis. Recent studies highlight the roles of exosomes and their miRNAs in intercellular communication, and the influence of uterine decidual microbiota on pregnancy outcomes.
Fengping He +6 more
wiley +1 more source
CellsDuring the secretory phase of the menstrual cycle, endometrial fibroblast cells begin to change into large epithelial-like cells called decidual cells in a process called decidualization. This differentiation continues more broadly in the endometrium and
Rupak Thapa +4 more
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Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues [PDF]
, 2009 Background It has been well established that prolactin (PRL) signals through the long form of its receptor (PRL-RL) and activates the Jak/Stat pathway for transcription of PRL target genes.
Y Sangeeta Devi +6 more
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Glycodelin-A primes zona pellucida-induced acrosome reaction of human spermatozoa via downregulation of extracellular signal regulated kinases and enhancement of zona pellucida-induced calcium influx [PDF]
, 2010 Conference Theme: The Intersection Between Genetics, Genomics, and Reproductive BiologypostprintThe 43rd Annual Meeting of the Society for the Study of Reproduction (SSR), Milwaukee, WI., 30 July-3 August 2010. In Meeting Abstracts, 2010, p. 38, abstract
Chiu, PCN +3 more
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The FASEB Journal, Volume 40, Issue 8, 30 April 2026.Graphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Xianlin Rao +3 more
wiley +1 more source
Participation of COX2/mPGES1/PGE2 in mouse and human endometrial stromal decidualization
BMC Veterinary ResearchBackground Prostaglandin E2 (PGE2) is vital for embryo implantation and decidualization. Whether COX2/mPGES1/PGE2 pathway is essential for mouse and human decidualization remains unclear.
Peng-Chao Wang +5 more
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Molecular Basis of Impaired Decidualization in the Eutopic Endometrium of Endometriosis Patients
CellsEndometriosis is a chronic gynecological disorder characterized by the presence of endometrial tissue outside the uterine cavity. A common feature of this pathology is the impaired decidualization of endometrial stromal cells, a critical process that ...
Alejandra Monserrat Retis-Resendiz +3 more
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Loss of miR-542-3p enhances IGFBP-1 expression in decidualizing human endometrial stromal cells [PDF]
, 2017 Endometrial decidualization represents an essential step for the successful implantation of the embryo; however, the molecular mechanism behind this differentiation process remains unclear.
Brosens, Jan J. +8 more
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G-protein coupled receptor 64 is required for decidualization of endometrial stromal cells
Scientific Reports, 2017 Although GPR64 has an important role for male fertility, its physiological roles in the female reproductive system are still unknown. In the present study, immunohistochemical analysis reveals a spatiotemporal expression of GPR64 in the uterus during ...
Jung-Yoon Yoo +6 more
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