Results 1 to 10 of about 244,301 (211)

Coordinated Role of Toll-Like Receptor-3 and Retinoic Acid-Inducible Gene-I in the Innate Response of Bovine Endometrial Cells to Virus [PDF]

open access: yesFrontiers in Immunology, 2017
Bovine herpesvirus-4 (BoHV-4) and bovine viral diarrhea virus (BVDV) infect the uterus of cattle, often resulting in reduced fertility, or abortion of the fetus, respectively. Here, exposure of primary bovine endometrial cells to BoHV-4 or BVDV modulated
Luisa C. Carneiro   +10 more
doaj   +4 more sources

Suppression of autophagy and HCK signaling promotes PTGS2high FCGR3− NK cell differentiation triggered by ectopic endometrial stromal cells

open access: yesAutophagy, 2018
Impaired NK cell cytotoxic activity contributes to the local dysfunctional immune environment in endometriosis (EMS), which is an estrogen-dependent gynecological disease that affects the function of ectopic endometrial tissue clearance.
Jie Mei   +2 more
exaly   +2 more sources

CD34+KLF4+ Stromal Stem Cells Contribute to Endometrial Regeneration and Repair

open access: yesCell Reports, 2019
Summary: The regenerative capacity of the human endometrium requires a population of local stem cells. However, the phenotypes, locations, and origin of these cells are still unknown.
Mingzhu Yin   +7 more
doaj   +2 more sources

Control of human endometrial stromal cell motility by PDGF-BB, HB-EGF and trophoblast-secreted factors [PDF]

open access: yes, 2013
Human implantation involves extensive tissue remodeling at the fetal-maternal interface. It is becoming increasingly evident that not only trophoblast, but also decidualizing endometrial stromal cells are inherently motile and invasive, and likely ...
A Brar   +85 more
core   +18 more sources

The effects of resveratrol on the expression of VEGF, TGF-β, and MMP-9 in endometrial stromal cells of women with endometriosis

open access: yesScientific Reports, 2021
Resveratrol is a phytochemical with anti-angiogenic, anti-inflammatory, and antioxidant properties. The present study has evaluated the effect of resveratrol on the expression of vascular endothelial growth factor (VEGF), transforming growth factor-β ...
Tahereh Arablou   +6 more
semanticscholar   +1 more source

From cup to dish: how to make and use endometrial organoid and stromal cultures derived from menstrual fluid

open access: yesFrontiers in Endocrinology, 2023
Diseases impacting the female reproductive tract pose a critical health concern. The establishment of in vitro models to study primary endometrial cells is crucial to understanding the mechanisms that contribute to normal endometrial function and the ...
Sylvia C. Hewitt   +5 more
doaj   +1 more source

Endometrial regeneration with endometrial epithelium: homologous orchestration with endometrial stroma as a feeder

open access: yesStem Cell Research & Therapy, 2021
Background Thin endometrium adversely affects reproductive success rates with fertility treatment. Autologous transplantation of exogenously prepared endometrium can be a promising therapeutic option for thin endometrium; however, endometrial epithelial ...
Ryo Yokomizo   +8 more
doaj   +1 more source

Transcriptomic analysis of human endometrial stromal cells during early embryo invasion

open access: yesAnnals of Medicine, 2021
Purpose During early embryo invasion (48 h after embryo attachment), what functional changes accompany dynamic gene expression alterations in human endometrial stromal cells?Method In the present study, primary human endometrial stromal cells (phESCs ...
Shuo Han, Minghui Liu, Shan Liu, Yuan Li
doaj   +1 more source

Single-cell RNA sequencing and lineage tracing confirm mesenchyme to epithelial transformation (MET) contributes to repair of the endometrium at menstruation

open access: yeseLife, 2022
The human endometrium experiences repetitive cycles of tissue wounding characterised by piecemeal shedding of the surface epithelium and rapid restoration of tissue homeostasis.
Phoebe M Kirkwood   +6 more
doaj   +1 more source

Endometrial stromal cells exhibit a distinct phenotypic and immunomodulatory profile

open access: yesStem cell research & therapeutics, 2020
In Asherman’s syndrome (AS), intrauterine scarring and fibrotic adhesions lead to menstrual disorders, pregnancy loss, or infertility. A few clinical trials have piloted cell therapy to overcome AS.
S. Queckbörner   +3 more
semanticscholar   +1 more source

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