Frontiers in Immunology, 2022 Decidualization of endometrial stromal cells and the presence of immunocompetent cells, including human mast cells, play important roles in the establishment of pregnancy.
Chiyuki Ueshima +12 more
doaj +1 more source
Matrix Metalloproteinases in Human Decidualized Endometrial Stromal Cells [PDF]
Current Issues in Molecular Biology, 2021 Cyclic changes, such as growth, decidualization, shedding, and regeneration, in the human endometrium are regulated by the reciprocal action of female hormones, such as estradiol (E2), and progesterone (P4). Matrix metalloproteases (MMPs) and tissue inhibitors of MMPs (TIMPs) control the invasion of extravillous trophoblast cells after implantation ...
Yoji Hisamatsu +6 more
openaire +3 more sources
Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss [PDF]
, 2012 Decidualization renders the endometrium transiently receptive to an implanting blastocyst although the underlying mechanisms remain incompletely understood.
Nicou, M +88 more
core +2 more sources
Stem cell-like properties of the endometrial side population: implication in endometrial regeneration. [PDF]
PLoS ONE, 2010 BACKGROUND: The human endometrium undergoes cyclical regeneration throughout a woman's reproductive life. Ectopic implantation of endometrial cells through retrograde menstruation gives rise to endometriotic lesions which affect approximately 10% of ...
Hirotaka Masuda +13 more
doaj +1 more source
Cell-type Phylogenetics and the Origin of Endometrial Stromal Cells
Cell Reports, 2015 A challenge of genome annotation is the identification of genes performing specific biological functions. Here, we propose a phylogenetic approach that utilizes RNA-seq data to infer the historical relationships among cell types and to trace the pattern of gene-expression changes on the tree.
Kin, Koryu +4 more
openaire +4 more sources
The mitogenic potential of heparin-binding epidermal growth factor in the human endometrium is mediated by the epidermal growth factor receptor and is modulated by tumor necrosis factor-alpha [PDF]
, 2002 Heparin-binding epidermal growth factor (HB-EGF), a member of the epidermal growth factor (EGF) family, is implicated in a variety of biological processes, including reproduction.
Mardon, Helen J. +23 more
core +1 more source
Effect of letrozole and raloxifene on in vitro human endometrial stromal cells [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020 Introduction: Letrozole and raloxifene are used in female reproductive disease. They have special properties and side-effects. This study was performed with aim to compare the in vitro effects of letrozole and raloxifene on human endometrial stromal ...
Maryam Pourheydar +2 more
doaj +1 more source
Icaritin inhibits decidualization of endometrial stromal cells
Experimental and Therapeutic Medicine, 2017 The aim of the present study was to investigate the effects of Icaritin on the proliferation and decidualization of endometrial stromal cells (ESCs). A total of 20 specimens of endometrium were collected during hysterectomy at the Gynecology Department of Shenzhen Nanshan People's Hospital (Shenzhen, China) between August 2014 and December 2015.
Le, Aiwen +7 more
openaire +3 more sources
PLoS ONE, 2013 BackgroundOur previous studies suggested that aberrant activation of Wnt/ß-catenin signaling might be involved in the pathophysiology of endometriosis.
Sachiko Matsuzaki, Claude Darcha
doaj +1 more source
NLRP7 contributes to in vitro decidualization of endometrial stromal cells [PDF]
Reproductive Biology and Endocrinology, 2017 Nucleotide-binding oligomerization domain (NACHT), leucine rich repeat (LRR) and pyrin domain (PYD) 7 containing protein, NLRP7, is a member of the NLR family which serves as innate immune sensors. Mutations and genetic variants of NLRP7 have been found in women with infertility associated conditions, such as recurrent hydatidiform mole, recurrent ...
Jyun-Yuan Huang +3 more
openaire +3 more sources