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Endometriosis is a common gynecological disease that affects approximately 5–10% of reproductive-aged women. However, the etiology and pathophysiology of endometriosis are currently unclear.
Chih-Chieh Chen +4 more
doaj +1 more source
Clinicoprognostical features of endometrial cancer patients with somatic mtDNA mutations [PDF]
Somatic mitochondrial DNA (mtDNA) mutations have been found in a subset of endometrial cancers (EC) from different populations. We have investigated the relationship between mtDNA changes and clinical and pathological variables of women affected by ...
Bartnik, Ewa +13 more
core +1 more source
Development of methods for the in-vitro assessment of the adipogenesis and immunogenicity of human multipotent mesenchymal stromal cells [PDF]
Adult mesenchymal stromal cells (MSCs) have enormous potential in tissue engineering and regenerative medicine applications. MSC have also been reported to be immune-privileged.
Aldridge, Andrew Robert
core +6 more sources
Objective This experimental study aimed to evaluate the effects of 17β-estradiol (E2) and progesterone (P4) on the interaction between mouse embryo and human endometrial mesenchymal stromal cells, and gene expressions related to implantation [αV and β3 ...
Marzieh Rahimipour +2 more
doaj +1 more source
Isolation and characterization of equine endometrial mesenchymal stromal cells [PDF]
Equine mesenchymal stromal/stem cells (MSCs) are most commonly harvested from bone marrow (BM) or adipose tissue, requiring the use of surgical procedures. By contrast, the uterus can be accessed nonsurgically, and may provide a more readily available cell source.
Rink, B Elisabeth +6 more
openaire +3 more sources
The androgen and progesterone receptors regulate distinct gene networks and cellular functions in decidualizing endometrium [PDF]
Progesterone is indispensable for differentiation of human endometrial stromal cells (HESCs) into decidual cells, a process that critically controls embryo implantation.
Cartwright, JE +44 more
core +1 more source
Differential Expression of CRH, UCN, CRHR1 and CRHR2 in Eutopic and Ectopic Endometrium of Women with Endometriosis. [PDF]
Endometriosis is considered as a benign aseptic inflammatory disease, characterised by the presence of ectopic endometrium-like tissue. Its symptoms (mostly pain and infertility) are reported as constant stressors.
Sabatini, Luca +13 more
core +2 more sources
Reciprocal Communication Between Endometrial Stromal Cells and Macrophages [PDF]
This study tested the hypothesis that reciprocal communication occurs between macrophages and cultured human endometrial stromal cells and that this communication may contribute to the pathology of endometriosis. An endometrial stromal cell line (telomerase-immortalized human endometrial stromal cell [T-HESC]) was treated with macrophage-conditioned ...
Kathleen M, Eyster +5 more
openaire +2 more sources
Patients with adenomyosis not only experience a decrease in quality of life as a result of dysmenorrhea and severe monthly flow but they are also rendered infertile.
Yuanquan Dai +3 more
doaj +1 more source
Bovine herpesvirus-4 (BoHV-4) and bovine viral diarrhea virus (BVDV) infect the uterus of cattle, often resulting in reduced fertility, or abortion of the fetus, respectively. Here, exposure of primary bovine endometrial cells to BoHV-4 or BVDV modulated
Luisa C. Carneiro +10 more
doaj +1 more source

