Results 41 to 50 of about 244,422 (325)

Hypoxia-Inducible Factor-1α Promotes Endometrial Stromal Cells Migration and Invasion by Upregulating Autophagy in Endometriosis

open access: yesReproduction, 2017
Endometriosis is a benign gynaecological disease which shares some characteristics with malignancy like migration and invasion. It has been reported that both Hypoxia-Inducible Factor-1α (HIF-1α) and autophagy were upregulated in ectopic endometrium of ...
Hengwei Liu   +8 more
semanticscholar   +1 more source

Effect of letrozole and raloxifene on in vitro human endometrial stromal cells [PDF]

open access: yesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020
Introduction: Letrozole and raloxifene are used in female reproductive disease. They have special properties and side-effects. This study was performed with aim to compare the in vitro effects of letrozole and raloxifene on human endometrial stromal ...
Maryam Pourheydar   +2 more
doaj   +1 more source

T-cadherin inhibits invasion and migration of endometrial stromal cells in endometriosis.

open access: yesHuman Reproduction, 2019
STUDY QUESTION What is the expression level of T-cadherin in endometriosis, and does T-cadherin play a role in regulating invasion and migration of endometrial stromal cells?
Qinsheng Lu   +15 more
semanticscholar   +1 more source

Icaritin inhibits decidualization of endometrial stromal cells

open access: yesExperimental and Therapeutic Medicine, 2017
The aim of the present study was to investigate the effects of Icaritin on the proliferation and decidualization of endometrial stromal cells (ESCs). A total of 20 specimens of endometrium were collected during hysterectomy at the Gynecology Department of Shenzhen Nanshan People's Hospital (Shenzhen, China) between August 2014 and December 2015.
Le, Aiwen   +7 more
openaire   +3 more sources

Estrogenicity of Isoflavones on Human Endometrial Stromal and Glandular Cells [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 2002
Endometrium consists of different cell populations such as epithelial and stromal cells and is mainly regulated by sex steroids. Isoflavones are plant-derived estrogenic compounds that have estrogenic and antiestrogenic properties in a cell-specific manner. We hypothesized that one of the potential health benefits of isoflavones may be their ability to
Umit A, Kayisli   +3 more
openaire   +2 more sources

SFRP4+ stromal cell subpopulation with IGF1 signaling in human endometrial regeneration

open access: yesCell Discovery, 2022
Our understanding of full-thickness endometrial regeneration after injury is limited by an incomplete molecular characterization of the cell populations responsible for the organ functions.
Bingbing Wu   +14 more
doaj   +1 more source

The transcriptomic evolution of mammalian pregnancy:gene expression innovations in endometrial stromal fibroblasts [PDF]

open access: yes, 2016
The endometrial stromal fibroblast (ESF) is a cell type present in the uterine lining of therian mammals. In the stem lineage of eutherian mammals, ESF acquired the ability to differentiate into decidual cells in order to allow embryo implantation.
Alyssa Birt   +16 more
core   +2 more sources

Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]

open access: yes, 2020
Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna   +8 more
core   +2 more sources

Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua

open access: yesCell Reports, 2021
Summary: Various human diseases and pregnancy-related disorders reflect endometrial dysfunction. However, rodent models do not share fundamental biological processes with the human endometrium, such as spontaneous decidualization, and no existing human ...
Virginia Chu Cheung   +8 more
doaj   +1 more source

Establishment of an immortalized human endometrial stromal cell line with functional responses to ovarian stimuli

open access: yesReproductive Biology and Endocrinology, 2011
Studies on the mechanisms of decidualization and endometriosis are often hampered by lack of primary endometrial cells. To facilitate in vitro studies, we established a human endometrial stromal cell line, KC02-44D, immortalized with human telomerase ...
Aoki Yuko   +4 more
doaj   +1 more source

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