Results 61 to 70 of about 244,422 (325)

Clinicoprognostical features of endometrial cancer patients with somatic mtDNA mutations [PDF]

open access: yes, 2014
Somatic mitochondrial DNA (mtDNA) mutations have been found in a subset of endometrial cancers (EC) from different populations. We have investigated the relationship between mtDNA changes and clinical and pathological variables of women affected by ...
Bartnik, Ewa   +6 more
core   +1 more source

Recurrent pregnancy loss is associated with a pro-senescent decidual response during the peri-implantation window [PDF]

open access: yes, 2020
During the implantation window, the endometrium becomes poised to transition to a pregnant state, a process driven by differentiation of stromal cells into decidual cells (DC).
Brighton, Paul (Paul J.)   +12 more
core   +1 more source

Regulation of the PI3K/Akt pathway during decidualization of endometrial stromal cells

open access: yesPLoS ONE, 2017
Infertility is constantly increasing in Canada, where 16% of Canadian couples are experiencing difficulty conceiving. It is thought that infertility can emanate from the dysregulated communication between the embryo and the maternal endometrium. In order
F. Fabi   +6 more
semanticscholar   +1 more source

An IGF1-expressing endometrial stromal cell population is associated with human decidualization

open access: yesBMC Biology, 2022
Background Decidualization refers to the process of transformation of endometrial stromal fibroblast cells into specialized decidual stromal cells that provide a nutritive and immunoprivileged matrix essential for blastocyst implantation and placental ...
Jia-Wei Shi   +11 more
doaj   +1 more source

Unique Molecular Features in High-Risk Histology Endometrial Cancers [PDF]

open access: yes, 2019
Endometrial cancer is the most common gynecologic malignancy in the United States and the sixth most common cancer in women worldwide. Fortunately, most women who develop endometrial cancer have low-grade early-stage endometrioid carcinomas, and simple ...
Collins, Kaitlyn   +4 more
core   +1 more source

Dysregulation of In Vitro Decidualization of Human Endometrial Stromal Cells by Insulin via Transcriptional Inhibition of Forkhead Box Protein O1

open access: yesPLoS ONE, 2017
Insulin resistance and compensatory hyperinsulinemia are characteristic features of obesity and polycystic ovary syndrome, and both are associated with reduced fertility and implantation.
D. Ujvari   +6 more
semanticscholar   +1 more source

Reciprocal Communication Between Endometrial Stromal Cells and Macrophages [PDF]

open access: yesReproductive Sciences, 2010
This study tested the hypothesis that reciprocal communication occurs between macrophages and cultured human endometrial stromal cells and that this communication may contribute to the pathology of endometriosis. An endometrial stromal cell line (telomerase-immortalized human endometrial stromal cell [T-HESC]) was treated with macrophage-conditioned ...
Kathleen M, Eyster   +5 more
openaire   +2 more sources

Molecular mechanism of aberrant decidualization in adenomyosis leading to reduced endometrial receptivity

open access: yesFrontiers in Endocrinology
Patients with adenomyosis not only experience a decrease in quality of life as a result of dysmenorrhea and severe monthly flow but they are also rendered infertile.
Yuanquan Dai   +3 more
doaj   +1 more source

Isolation of Human Endometrial Stromal Cells for In Vitro Decidualization.

open access: yesJournal of Visualized Experiments, 2018
The differentiation of human endometrial stromal cells (HESC) from fibroblast-like appearance into secretory decidua is a transformation required for embryo implantation into the uterine lining of the maternal womb.
Stephanie Michalski   +3 more
semanticscholar   +1 more source

Transcriptomic responses to hypoxia in endometrial and decidual stromal cells [PDF]

open access: yesReproduction, 2019
Abstract Human reproductive success depends on a properly decidualized uterine endometrium that allows implantation and the formation of the placenta. At the core of the decidualization process are endometrial stromal fibroblasts (ESF) that differentiate to decidual stromal cells (DSC).
Rytkönen, Kalle T.   +7 more
openaire   +4 more sources

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