Results 51 to 60 of about 244,422 (325)

Response of xenografts of developing human female reproductive tracts to the synthetic estrogen, diethylstilbestrol. [PDF]

, 2017
Human female fetal reproductive tracts 9.5-22 weeks of gestation were grown for 1 month in ovariectomized athymic adult female mouse hosts that were either untreated or treated continuously with diethylstilbestrol (DES) via subcutaneous pellet.
Baskin, Laurence, Cao, Mei, Cunha, Gerald R, Kurita, Takeshi, Robboy, Stanley J, Shen, Joel   +5 more
core   +2 more sources

Long non‐coding RNA MALAT1 mediates hypoxia‐induced pro‐survival autophagy of endometrial stromal cells in endometriosis

Journal of Cellular and Molecular Medicine, 2018
Endometriosis is a common gynecological disease characterized by diminished apoptosis, sustained ectopic survival of dysfunctional endometrial cells. Hypoxia has been implicated as a crucial microenvironmental factor that contributes to endometriosis. It
Hengwei Liu, Zhibing Zhang, Wenqian Xiong, Ling Zhang, Yu Du, Yi Liu, Xingao Xiong   +6 more
semanticscholar   +1 more source

Exosomes Derived from Umbilical Cord Mesenchymal Stem Cells Alleviate Mifepristone-Induced Human Endometrial Stromal Cell Injury

Stem Cells International, 2020
The human endometrial stromal cells (hEndoSCs) could maintain endometrial homeostasis and play a critical role in repairing endometrial injury. Mesenchymal stem cells (MSCs) significantly increase the proliferation of damaged hEndoSCs and protect them ...
Jianye Wang, Ruomeng Hu, Q. Xing, Xinghao Feng, Xiaohua Jiang, Yuping Xu, Zhaolian Wei   +6 more
semanticscholar   +1 more source

Transcriptome Profiling of Eutopic and Ectopic Endometrial Stromal Cells in Women with Endometriosis Based on High-Throughput Sequencing

Biomedicines, 2022
Endometriosis is a common gynecological disease that affects approximately 5–10% of reproductive-aged women. However, the etiology and pathophysiology of endometriosis are currently unclear.
Chih-Chieh Chen, Yung-Che Chou, Chia-Yi Hsu, Eing-Mei Tsai, Tze-Kiong Er   +4 more
doaj   +1 more source

Reproducibility of lymphovascular space invasion (LVSI) assessment in endometrial cancer [PDF]

, 2019
Aims Lymphovascular space invasion (LVSI) in endometrial cancer (EC) is an important prognostic variable impacting on a patient's individual recurrence risk and adjuvant treatment recommendations.
Bartosch, Carla, Bosse, Tjalling, Genestie, Catherine, Lax, Sigurd F, McCluggage, W Glenn, Nout, Remi, Oosting, Jan, Peters, Elke E M, Singh, Naveena, Smit, Huub C S H, Smit, Vincent T H B M, Van de Vijver, Koen   +11 more
core   +2 more sources

Metformin inhibits estradiol and progesterone-induced decidualization of endometrial stromal cells by regulating expression of progesterone receptor, cytokines and matrix metalloproteinases.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019
BACKGROUND Polycystic ovary syndrome (PCOS) is a serious threat for reproductive-aged women. Metformin has been used for the treatment of PCOS. However, its molecular mechanism in decidualization process of PCOS has not been well featured.
Fang Xiong, Juxia Xiao, Yinyang Bai, Yun Zhang, Qiuping Li, Xu Lishuang   +5 more
semanticscholar   +1 more source

Morphological, Ultrastructural, and Molecular Aspects of In Vitro Mouse Embryo Implantation on Human Endometrial Mesenchymal Stromal Cells in The Presence of Steroid Hormones as An Implantation Model

Cell Journal, 2018
Objective This experimental study aimed to evaluate the effects of 17β-estradiol (E2) and progesterone (P4) on the interaction between mouse embryo and human endometrial mesenchymal stromal cells, and gene expressions related to implantation [αV and β3 ...
Marzieh Rahimipour, Mojdeh Salehnia, Mina Jafarabadi   +2 more
doaj   +1 more source

The conceptus induces a switch in protein expression and activities of superoxide dismutase 1 and 2 in the sheep endometrium during early pregnancy [PDF]

, 2016
Acknowledgements We thank Philippe Bolifraud (INRA, France), Krawiec Angele, Sandra Grange, Laurence Puillet-Anselme (CHU Grenoble, France) and Margaret Fraser (Aberdeen, UK) for their expert technical assistance.
Al-Gubory, K. H., Fowler, P. A., Garrel, C., Sugino, N.   +3 more
core   +2 more sources

Ghrelin Is Involved in the Decidualization of Human Endometrial Stromal Cells [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2003
Successful implantation involves a complex interaction between the endometrium and the embryo. It is well known that several neuropeptides are expressed in the endometrium and placenta during embryonal implantation, suggesting an important role as chemical mediators of the feto-maternal relationship.
Keisuke, Tanaka, Hiroyuki, Minoura, Tetsuya, Isobe, Hitoshi, Yonaha, Hiroaki, Kawato, Dong Fang, Wang, Toshimichi, Yoshida, Masayasu, Kojima, Kenji, Kangawa, Nagayasu, Toyoda   +9 more
openaire   +2 more sources

USP10 promotes proliferation and migration and inhibits apoptosis of endometrial stromal cells in endometriosis through activating the Raf-1/MEK/ERK pathway.

American Journal of Physiology - Cell Physiology, 2018
Endometriosis has been initially described as endometrial-like tissue outside of the uterine cavity. The mitogen-activated protein kinase/ERK kinase (MEK)/extracellular signal-regulated kinase (ERK) signaling pathway playing an important role in the ...
Qiong Chen, Yuanyuan Hang, Tingting Zhang, Li Tan, Shuangdi Li, Yuli Jin   +5 more
semanticscholar   +1 more source