Results 71 to 80 of about 4,542,677 (277)

Angiogenesis Following Three-Dimensional Culture of Isolated Human Endometrial Stromal Cells [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2008
Background Endometriosis is the presence of endometrial tissue outside of the uterine cavity and is the most common gynecologic disorder in women of reproductive age.
Navid Esfandiari   +4 more
doaj   +1 more source

High-Grade Endometrial Stromal Sarcoma: Molecular Alterations and Potential Immunotherapeutic Strategies

open access: yesFrontiers in Immunology, 2022
Endometrial stromal tumor (EST) is an uncommon and unusual mesenchymal tumor of the uterus characterized by multicolored histopathological, immunohistochemical, and molecular features. The morphology of ESTs is similar to normal endometrial stromal cells
Youngah Kim   +4 more
doaj   +1 more source

Estrogenicity of Isoflavones on Human Endometrial Stromal and Glandular Cells [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 2002
Endometrium consists of different cell populations such as epithelial and stromal cells and is mainly regulated by sex steroids. Isoflavones are plant-derived estrogenic compounds that have estrogenic and antiestrogenic properties in a cell-specific manner. We hypothesized that one of the potential health benefits of isoflavones may be their ability to
Umit A, Kayisli   +3 more
openaire   +2 more sources

Lactobacillus‐Loaded Bioadhesive Hydrogel with Prolonged Retention and Microenvironmental Remodeling for Endometrial Repair and Fertility Restoration

open access: yesAdvanced Science, EarlyView.
A bioactive adhesive hydrogel capable of long‐term uterine retention (>14 days) and local microenvironment modulation is developed by straightforward integration of α‐lipoic acid, L‐arginine, tannic acid, and Lactobacillus johnsonii, which can markedly enhance endometrial repair and restore fertility in a rat model of endometrial injury.
Lifa Chen   +9 more
wiley   +1 more source

Human endometrial side population cells exhibit genotypic, phenotypic and functional features of somatic stem cells. [PDF]

open access: yesPLoS ONE, 2010
During reproductive life, the human endometrium undergoes around 480 cycles of growth, breakdown and regeneration should pregnancy not be achieved.
Irene Cervelló   +15 more
doaj   +1 more source

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

open access: yesAdvanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao   +19 more
wiley   +1 more source

Progesterone action in the myometrium and decidua in preterm birth [PDF]

open access: yes, 2012
Progesterone is central to many reproductive processes and is critical in regulating the menstrual cycle and maintaining pregnancy. We discuss here similarities in the molecular mechanisms that regulate the process of decidualisation in endometrial ...
Blanks, Andrew M., Brosens, Jan J.
core  

Adipose-derived mesenchymal stromal/stem cells : tissue localization, characterization, and heterogeneity [PDF]

open access: yes, 2012
Adipose tissue as a stem cell source is ubiquitously available and has several advantages compared to other sources. It is easily accessible in large quantities with minimal invasive harvesting procedure, and isolation of adipose-derived mesenchymal ...
Helmut Geiger   +3 more
core   +1 more source

Characterization of signalling cross-talk between the EP2 and FP receptors in endometrial epithelial cells [PDF]

open access: yes, 2009
Uterine fibroids are benign tumors that arise from the smooth-muscle uterine cells (myometrium) and are the most common uterine disorder occurring in as many as 30% of women over 35 years of age. Despite their frequent occurrence, the etiology of uterine
Abera, Aron Berhanie
core   +1 more source

A Novel Marker of Human Endometrial Mesenchymal Stem-Like Cells

open access: yesCell Transplantation, 2012
Coexpression of CD140b (PDGFRβ) and CD146 has been used to isolate endometrial mesenchymal stem-like cells (eMSCs), which have a perivascular location. This study aims to evaluate a single marker for purifying eMSCs.
Hirotaka Masuda   +4 more
doaj   +1 more source

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