Results 91 to 100 of about 244,422 (325)

Angiogenesis Following Three-Dimensional Culture of Isolated Human Endometrial Stromal Cells [PDF]

International Journal of Fertility and Sterility, 2008
Background Endometriosis is the presence of endometrial tissue outside of the uterine cavity and is the most common gynecologic disorder in women of reproductive age.
Navid Esfandiari, Mozafar Khazaei, Zohreh Nazemian, Aaron Jolly, Robert F. Casper   +4 more
doaj   +1 more source

High-Grade Endometrial Stromal Sarcoma: Molecular Alterations and Potential Immunotherapeutic Strategies

Frontiers in Immunology, 2022
Endometrial stromal tumor (EST) is an uncommon and unusual mesenchymal tumor of the uterus characterized by multicolored histopathological, immunohistochemical, and molecular features. The morphology of ESTs is similar to normal endometrial stromal cells
Youngah Kim, Youngah Kim, Dohyang Kim, Woo Jung Sung, Jaewoo Hong   +4 more
doaj   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Human endometrial side population cells exhibit genotypic, phenotypic and functional features of somatic stem cells. [PDF]

PLoS ONE, 2010
During reproductive life, the human endometrium undergoes around 480 cycles of growth, breakdown and regeneration should pregnancy not be achieved.
Irene Cervelló, Irene Cervelló, Claudia Gil-Sanchis, Aymara Mas, Francisco Delgado-Rosas, José Antonio Martínez-Conejero, Amparo Galán, Alicia Martínez-Romero, Sebastian Martínez, Ismael Navarro, Jaime Ferro, José Antonio Horcajadas, Francisco José Esteban, José Enrique O'Connor, Antonio Pellicer, Carlos Simón   +15 more
doaj   +1 more source

Endometrial Stromal Sarcoma Presenting As Puberty Menorrhagia [PDF]

, 2005
Endometrial stromal sarcomas are rare uterine tumours usually seen in perimenopausal females. We report here a case of low grade malignant endometrial stromal sarcoma in an adolescent girl, presenting as puberty menorrhagia.
Prabhakaran Nair, Rema, Sebastian, Paul
core   +1 more source

Local Remodeling of Synthetic Extracellular Matrix Microenvironments by Co-cultured Endometrial Epithelial and Stromal Cells Enables Long-term Dynamic Physiological Function

Integrative Biology, 2017
Mucosal barrier tissues, comprising a layer of tightly-bonded epithelial cells in intimate molecular communication with an underlying matrix-rich stroma containing fibroblasts and immune cells, are prominent targets for drugs against infection, chronic ...
C. Cook, A. Hill, M. Guo, L. Stockdale, Julia P. Papps, K. Isaacson, D. Lauffenburger, L. Griffith   +7 more
semanticscholar   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

A Novel Marker of Human Endometrial Mesenchymal Stem-Like Cells

Cell Transplantation, 2012
Coexpression of CD140b (PDGFRβ) and CD146 has been used to isolate endometrial mesenchymal stem-like cells (eMSCs), which have a perivascular location. This study aims to evaluate a single marker for purifying eMSCs.
Hirotaka Masuda, Siti S. Anwar, Hans-Jörg Bühring, Jyothsna R. Rao, Caroline E. Gargett Ph.D.   +4 more
doaj   +1 more source

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

Low-grade endometrial stromal sarcoma: A report of five cases

Archives of Medicine and Health Sciences, 2018
Endometrial stromal sarcoma (ESS) is a very rare uterine tumor, composed of cells resembling endometrial stromal cells. As these tumors have indistinct clinical and radiological features, they are very rarely diagnosed preoperatively.
Saba Bashir, Prema Saldanha
doaj   +1 more source