Results 101 to 110 of about 244,422 (325)

Isolation of Mouse Endometrial Epithelial and Stromal Cells for In Vitro Decidualization

Journal of Visualized Experiments, 2017
Decidualization is a progesterone-dependent differentiation process of endometrial stromal cells and is a prerequisite for successful embryo implantation.
K. De Clercq, Aurélie Hennes, J. Vriens
semanticscholar   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

The features of mesenchimal stromal cells of normal endometrium and endometrium from patients with different gynecological diseases

RUDN Journal of Medicine, 2013
This is the only experimental study that offers mechanical isolation of stromal cells from normal endometrium and endometrium from patients with adenomyosis, uterine myoma and endometrial hyperplasia.
T A Anikina, V E Radzinsky, K A Rubina, V Yu Sysoeva   +3 more
doaj  

Metformin reduces androgen receptor and upregulates homeobox A10 expression in uterine endometrium in women with polycystic ovary syndrome

Reproductive Biology and Endocrinology, 2021
Background Polycystic ovary syndrome (PCOS) causes anovulation and is associated with a reduced clinical pregnancy rate. Metformin, which is widely used for treating PCOS, can lead to successful pregnancy by restoring the ovulation cycle and possibly ...
Miki Ohara, Hiromi Yoshida-Komiya, Miho Ono-Okutsu, Akiko Yamaguchi-Ito, Toshifumi Takahashi, Keiya Fujimori   +5 more
doaj   +1 more source

IL-15 Regulation in Human Endometrial Stromal Cells [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2002
A greater knowledge of IL-5 regulation within human endometrium is important in understanding key reproductive events and uterine Natural Killer cell function. In the present study, expression of IL-15 mRNA was shown to be up-regulated by both PGE(2) and IFN-gamma in cultures of human endometrial stromal cells (ESC).
Carolyn L, Dunn, Hilary O D, Critchley, Rodney W, Kelly   +2 more
openaire   +2 more sources

A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions

Animal Models and Experimental Medicine, EarlyView.
To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang, Yan Zan, Tiantian Ma, Xiaoquan Huang, Junwei Li, Liangjun Xia, Yuping Sa, Youbing Xia   +7 more
wiley   +1 more source

Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis

Reproductive Biology and Endocrinology
Background Patients with endometriosis suffer with chronic pelvic pain and infertility, and from the lack of pharmacologic therapies that consistently halt disease progression. Differences in the endometrium of patients with endometriosis vs.
Julia Delenko, Xiangying Xue, Prodyot K Chatterjee, Nathaniel Hyman, Andrew J Shih, Robert P Adelson, Polona Safaric Tepes, Peter K Gregersen, Christine N Metz   +8 more
doaj   +1 more source

Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide [PDF]

, 2015
Infection with noncytopathic bovine viral diarrhea virus (ncpBVDV) is associated with uterine disease and infertility. This study investigated the influence of ncpBVDV on immune functions of the bovine endometrium by testing the response to bacterial ...
Abudureyimu, A, Anstaett, O L, Brownlie, J, Cheng, Z R, Fouladi-Nashta, A A, Oguejiofor, C F, Wathes, D C   +6 more
core   +2 more sources

Effects of COH on the expression of connexin43 in endometrial stromal cells

Taiwanese Journal of Obstetrics and Gynecology, 2019
The purpose of this study was to investigate the effect of controlled ovarian hyperstimulation (COH) on gap junction, and to induce the effect of an estrogen level overdose on gap junction in vitro by COH. Here, we mainly focus on connexion43 (Cx43), progesterone receptor (PR) and prolactin-related protein (PRP), and CyclinD3 genes expression, as well ...
Guolin Liu, Yuanyuan Tang, Yibing Han, Xiaoming Teng   +3 more
openaire   +3 more sources

G-protein coupled receptor 64 is required for decidualization of endometrial stromal cells

Scientific Reports, 2017
Although GPR64 has an important role for male fertility, its physiological roles in the female reproductive system are still unknown. In the present study, immunohistochemical analysis reveals a spatiotemporal expression of GPR64 in the uterus during ...
Jung-Yoon Yoo, Jong Il Ahn, Tae Hoon Kim, Sungryul Yu, Ji Yeon Ahn, Jeong Mook Lim, Jae-Wook Jeong   +6 more
doaj   +1 more source