Results 121 to 130 of about 4,542,677 (277)

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

open access: yesPhytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan   +8 more
wiley   +1 more source

Prospective isolation of human bone marrow stromal cell subsets: a comparative study between Stro-1-, CD146- and CD105-enriched populations

open access: yes, 2014
Stro-1 has proved an efficacious marker for enrichment of skeletal stem and progenitor cells although isolated populations remain heterogeneous, exhibiting variable colony-forming efficiency and osteogenic differentiation potential. The emerging findings
Greenhough, Joanna   +7 more
core   +1 more source

Impact of a Chinese Medicinal Formula, Xiao Liu Fang, on the “3A” Ability of Endometrial Stromal Cells in Patients with Endometriosis

open access: yesMolecular Therapy: Oncolytics, 2019
The pathogenesis of endometriosis (EMS) is complicated, and treatment results are unsatisfactory. It has become the focus of gynecological research. Analysis targeting the pathogenesis of EMS is the key to providing more effective treatments.
Hua Zhou, Qian Zhang, Cong Qi
doaj   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi   +5 more
wiley   +1 more source

Regeneration capacity of the endometrium: endometrial stem cells

open access: yes, 2016
Ege Üniversitesi, Tıp FakültesiEndometrium her ay gerçekleşen çoğalma ve dejenerasyon döngüsü nedeniyle postpubertal ve premenopozal dönemler arasında yüksek bir rejenerasyon kapasitesine sahiptir.
Şahin, Çağdaş   +2 more
core   +1 more source

Proliferative Potential of Endometrial Stromal Cells, and Endometrial and Placental Expression of Cyclin in the Bovine

open access: yesJournal of Reproduction and Development, 2003
The objective of the present investigation was to study proliferative activity of fibroblast-like endometrial stromal cells in bovine endometrial caruncular (CAR) and intercaruncular (ICAR) areas that have distinct functions during implantation. Endometrial stromal cells were derived from CAR and ICAR of nonpregnant cows, and their proliferative ...
YAMAUCHI, Nobuhiko   +4 more
openaire   +3 more sources

Diflubenzuron Caused Mitochondrial Dysfunction, Ca2+ Homeostasis Disruption, and Intrinsic Apoptosis in Trophoblastic Cells

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Diflubenzuron is used as an insect growth inhibitor, and its potential risk to human health was raised owing to the possibility of environmental residues and human exposure. This study aimed to investigate the toxic mechanism of diflubenzuron on trophoblastic cells such as HTR8/SVneo and JEG‐3 cells. We investigated mitochondrial function, Ca2+
Miji Kim   +4 more
wiley   +1 more source

Role of decidual corticosteroid production in reproductive failure [PDF]

open access: yes
Glucocorticoids have been implicated in many processes including successful embryo implantation, placentation, and the growth and development of the fetus.
Venkatakrishnan, R.
core  

Mitochondria remodeling during endometrial stromal cell decidualization

open access: yesLife Science Alliance
Upon hormonal stimulation, uterine endometrial stromal cells undergo a dramatic morpho-functional metamorphosis that allows them to secrete large amounts of matrix proteins, cytokines, and growth factors. This step, known as decidualization, is crucial for embryo implantation.
Marco Dalla Torre   +5 more
openaire   +2 more sources

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue   +3 more
wiley   +1 more source

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