Results 111 to 120 of about 1,667,357 (297)

Investment Decision Making With Investment Satisfaction As An Intervening Variable: Availability Bias And Financial Literacy

, 2023
Ayundha Evanthi, Ira Wikartika, Rahman Amrullah Suwaidi   +2 more
openalex   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Temporal characteristics of the human mirror neuron system. Research using transcranial magnetic stimulation

Нервно-мышечные болезни
Background. Mirror neurons (MN) are integral to linking the perception of actions with their execution, activating during both action observation and execution.
K. Nieto-Doval, A. A. Ragimova, A. O. Vyazmin, O. I. Shevtsov, M. Feurra   +4 more
doaj   +1 more source

Providing Seasonal-to-Interannual Climate Information for Risk Management and Decision-making

, 2010
Lisa Goddard, Youcef Ait‐Chellouche, Walter Baethgen, Michael D. Dettinger, Richard Graham, Peter Hayman, M. Ait Kadi, Rodney Martínez, Holger Meinke   +8 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Patient readiness for shared decision making about treatment: Conceptualisation and development of the ReadySDM

Health Expectations
Introduction Shared decision making (SDM) requires an active role of both clinicians and patients. We aimed to conceptualise patient readiness for SDM about treatment, and to develop a patient questionnaire to assess readiness.
Sascha M. Keij, Anne M. Stiggelbout, Arwen H. Pieterse   +2 more
doaj   +1 more source

Ethical and Interpretable AI Systems for Decision-Making in Autonomous Infrastructure Management [PDF]

Shivani Choudhary
openalex   +1 more source

Decision making [PDF]

Current Biology, 2005
openaire   +2 more sources