Results 191 to 200 of about 1,667,357 (297)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Control Policy and Sustainability for Decision-Making in Asset Management [PDF]

, 2020
Tolulope Latunde, Adebayo Funmi Adedotun, Joel Olusegun Ajinuhi, Yemi Tolulope Owolabi, Adam Ajimoti Ishaq   +4 more
openalex  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Mathematical Oncology: How Modeling Is Transforming Clinical Decision-Making. [PDF]

Cancer Res
Scibilia KR, Gallagher K, Masud MA, Robertson-Tessi M, Gatenbee CD, West J, Llamas P, Prabhakaran S, Gallaher J, Anderson ARA.   +9 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Shared Decision-Making. A Primer for Clinicians. [PDF]

J Gen Intern Med
Elwyn G, Gulbrandsen P, Leavitt H, Abukmail E, Clayman ML, Edwards A, Finderup J, Fisher A, Grande SW, Hahlweg P, Hoffmann T, Hou WH, Hernández-Leal MJ, Leung D, Lu W, Mandelkow L, Pecanac KE, Pieterse AH, Price A, Rabben J, Riganti P, Sanatani M, Scheibler F, Schoefs E, Taylor OA, Valentine KD, Wexler R.   +26 more
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Distributionally robust free energy principle for decision-making. [PDF]

Nat Commun
Shafiei A, Jesawada H, Friston K, Russo G.   +3 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Elderly Patients with Non-ST-Elevation Acute Coronary Syndrome: A Proposal to Adapt Decision Making

, 2015
B Alvarez
openalex   +1 more source