Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Topological Derivative-Based Topology Optimization of Linearized Viscous Shallow Water Equation
In this paper, we focus on the derivation of the topological derivative of shallow water equations. We consider two-dimensional viscous shallow-water equations linearized around a constant velocity.
Mame Gor Ngom +3 more
doaj +1 more source
On Ordinal Information-Based Weighting Methods and Comparison Analyses
In this paper, we focus on weighting methods within multi-attribute utility/value theory (MAUT/MAVT). In these methods, the decision maker (DM) provides ordinal information about the relative importance of criteria, but also additional information ...
Zhor Chergui, Antonio Jiménez-Martín
doaj +1 more source
A Case Study for Design Decisions on Building Service System using LCC Analysis [PDF]
Seung-Bok Leigh, Jong-Seo Won
openalex +1 more source
Risk and Uncertainty Analysis with Networks of Decisions [PDF]
In this paper an applied approach for analysing economic problems under risk and uncertainty based on networks of decisions (NODs) will be discussed. It can be shown that network of decision analysis can help to understand complex decision problems under
Recke, Guido
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Decision analysis for seabird recovery: Navigating complexity across ecosystems, balancing competing values and bridging spaces between research and implementation [PDF]
Johannes H. Fischer +11 more
openalex +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Analysis Of The Impact Of Wheat Farmers Decisions Under Risk In Egypt [PDF]
Zaki Saad +14 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

