Results 101 to 110 of about 21,698,220 (290)
Credal Sum-Product Networks [PDF]
, 2017 Sum-product networks are a relatively new and increasingly popular class of (precise) probabilistic graphical models that allow for marginal inference with polynomial effort. As with other probabilistic models, sum-product networks are often learned from
Decision Support Systems +6 more
core +1 more source
A review of clinical decision-making: Models and current research [PDF]
, 2007 Aims and objectives: The aim of this paper was to review the current literature with respect to clinical decision-making models and the educational application of models to clinical practice.
Banning, M, Maggi Banning
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Decision support systems [PDF]
Decision Support Systems (DSS) are a specific class of computerized information system that supports business and organizational decision-making activities.
Georgiana MARIN
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Higher education decision making and decision support systems [PDF]
The authors illustrate several issues in decision support and decision support systems (DSS), state of the art research in these fields, and also their own studies in designing a higher education DSS.
Ghisoiu, Nicolae +1 more
core
Arguing to motivate decisions [PDF]
, 2011 Decision makers often have to make difficult trade-offs in situations where multiple aspects matter that are different by nature. For example, in a crisis scenario with a big fire in a factory, trade-offs may have to be made between the safety of the ...
Decision Support Systems +3 more
core +1 more source
پیاورد سلامت, 2020 Background and Aim: When clinical decision support systems are developed, implementing solutions that enable these systems to be -used on a large scale can reduce the production costs associated with the creation, maintenance and by sharing these systems,
Azita Yazdani +4 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source