Results 91 to 100 of about 589,953 (289)

Bayesian networks for mastitis management on dairy farms

, 2009
This manuscript presents the idea of providing dairy farmers with probability distributions to support decisions on mastitis management and illustrates its feasibility by two applications. Naive Bayesian networks were developed for both applications. The
Barkema, H.W., Decision Support Systems, van der Gaag, M.A., Gaag, M.A., van der, Steeneveld, Wilma, van der Gaag, Linda, Steeneveld, W., Sub Decision Support Systems begr 1/1/13, Hogeveen, H.   +8 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Providing probability distributions for the Gram-status of clinical mastitis cases in dairy cattle

, 2009
Clinical mastitis (CM) can be caused by a wide variety of pathogens and a farmer has to start treatment before the actual causal pathogen is known. Knowing the Gram-status of CM cases would aid in the decision for the most appropriate treatment.
Lokhorst, C., Barkema, H.W., Decision Support Systems, Wolfert, S., Bregt, A., Wien, J.E., Steeneveld, Wilma, van der Gaag, Linda, Sub Decision Support Systems begr 1/1/13, Hogeveen, H.   +9 more
core  

Early development of decision support systems based on artificial intelligence: an application to postoperative complications and a cross-specialty reporting guideline for early-stage clinical evaluation

Background: Complications after major surgery occur in a similar manner internationally but the success of response process in preventing death varies widely depending on speed and appropriateness. Artificial intelligence (AI) offers new opportunities to
Vasey, Baptiste
core   +1 more source

Clinical decision support systems for maternity care: a systematic review and meta-analysis [PDF]

Background The use of Clinical Decision Support Systems (CDSS) is increasing throughout healthcare and may be able to improve safety and outcomes in maternity care, but maternity care has key differences to other disciplines that ...
Osborne, Cristina, South, Matthew; id_orcid, South, Matthew, Elsmore, Amy, Chandan, Joht Singh; id_orcid, Taylor, Beck, Nirantharakumar, Krishnarajah, Cockburn, Neil, Nanjappa, Ramya, Withana, Supun, Parry-Smith, William, Chandan, Joht Singh   +11 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Optimizing nursing clinical decision support systems: Insights from nurses’ experiences

Health Informatics Journal
Purpose This study explores nurses’ experiences with a Nursing Clinical Decision Support System (Nu-CDSS) two years post-implementation and identifies user-centered areas for system optimization. Methods A descriptive qualitative study was conducted in a
Qi Zhang MSN, Aliaya Adili BSN, Zhenghong Yu BSN, Wei Qin BSN, Zheng Zhu PhD, Yuxia Zhang PhD   +5 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

External validation of the DAYS score for suspected deep vein thrombosis

Research and Practice in Thrombosis and Haemostasis
Background: Diagnosing deep vein thrombosis (DVT) involves clinical assessment, D-dimer testing, and imaging. The DAYS score, a novel 2-item prediction tool combined with D-dimer, demonstrated promising performance but required external validation ...
Thor–David Halstensen, Camilla Hardeland, Waleed Ghanima, Vigdis Abrahamsen Grøndahl, Aliaksandr Hubin, Camilla Tøvik Jørgensen, Kerstin de Wit, Mazdak Tavoly   +7 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source