Results 151 to 160 of about 648,136 (315)
A Model for an Intelligent Support Decision System in Aquaculture
The paper purpose an intelligent software system agents–based to support decision in aquculture and the approach of fish diagnosis with informatics methods, techniques and solutions. A major purpose is to develop new methods and techniques for quick fish
Novac Ududec, Cornelia / C
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Multimedia and Decision-Making Process [PDF]
Multimedia technology has changed the way we use computers. Multimedia transforms com-puters into a second person. Multimedia technology has made it possible for us to see, hear, read, feel, and talk to computers.
Ovidiu-Alin DOBRICAN
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 2015 Low energy building retrofit presents important opportunities for reducing of greenhouse gas emissions in the environment. It has been considered as one of the key approaches to achieving sustainable development in construction industry.
Greenwood, David +2 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Spatial decision support for urban and environmental planning : a collection of case studies
, 2016 In the last decade, planners around the world have begun to develop and use spatial decision support systems (SDSS) and planning support systems (PSS) in their professional work.
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Decision Support Techniques for determination of the causal relationship between health problems of workers and their work activities. [PDF]
Rev Bras Med TrabMartins DA, Vianna DS, Dianin Vianna MF.
europepmc +1 more source