Results 191 to 200 of about 14,247 (218)

Stimulated expression of decorin and the decorin gene in fibroblasts cultured from patients with localized scleroderma

Archives of Dermatological Research, 1995
Decorin mRNA levels, the content of decorin and the synthesis of dermatan sulphate in skin fibroblasts from patients with systemic and localized scleroderma were investigated. Approximately a 2.2-fold increase in decorin mRNA levels, was found by Northern blot analysis in localized scleroderma, but no significant changes were found in systemic ...
T, Izumi, S, Tajima, T, Nishikawa
openaire   +2 more sources

A role for decorin in the remodeling of myocardial infarction

Matrix Biology, 2005
Because the small leucine-rich proteoglycan decorin has been implicated in regulation of collagen fibrillogenesis leading to proper extracellular matrix assembly, we hypothesized it could play a key role in cardiac fibrosis following myocardial infarction.
Sara M, Weis, Scott D, Zimmerman, Maithili, Shah, James W, Covell, Jeffrey H, Omens, John, Ross, Nancy, Dalton, Ying, Jones, Charles C, Reed, Renato V, Iozzo, Andrew D, McCulloch   +10 more
openaire   +2 more sources

Ageing-associated endothelial decorin induction and the impact of non-glycanated decorin on cardiac inflammation

Cardiovascular Research
Abstract Aims Cardiovascular disease is the leading cause of death in the European Union and ageing is one of its major risk factors resulting in the progressive deterioration of the cardiac structures and function.
Guillermo Luxán, Timm Winkelmeier, Colin Bodemer, Büşra Nur Toğru, Mariana Shumliakivska, Marion Muhly-Reinholz, Ariane Fischer, Mariano Ruz Jurado, David John, Wesley T Abplanalp, Stefanie Dimmeler   +10 more
openaire   +2 more sources

Decorin expression in quiescent myogenic cells

Biochemical and Biophysical Research Communications, 2008
Satellite cells are quiescent muscle stem cells that promote postnatal muscle growth and repair. When satellite cells are activated by myotrauma, they proliferate, migrate, differentiate, and ultimately fuse to existing myofibers. The remainder of these cells do not differentiate, but instead return to quiescence and remain in a quiescent state until ...
Takanori, Nishimura, Kenjiro, Nozu, Yasuhiro, Kishioka, Jun-Ichi, Wakamatsu, Akihito, Hattori   +4 more
openaire   +2 more sources

Decorin in the spatial control of collagen mineralization

Materials Horizons
Both COL I and pCOL I fibrils undergo nonhierarchical and hierarchical intrafibrillar mineralization in the PLIP system, respectively. However, DCN disrupts the mineralization process, indicating the inhibition of DCN in collagen mineralization.
Yuming Bai, Peng Wu, Qiufang Zhang, Feng Lin, Ling Hu, Zhisheng Zhang, Wenxia Huang, Yin Xiao, Qiliang Zuo   +8 more
openaire   +5 more sources

Structural Change in Decorin with Skin Aging

Connective Tissue Research, 2006
Decorin, the main proteoglycan in skin, has a small size with a core protein of approximately 40kDa and one chondroitin sulfate/dermatan sulfate glycosaminoglycan (GAG) chain. The main function of decorin is to regulate the collagen matrix assembly. Decorin is distributed along collagen fibrils with the core protein and the decorin GAG chain controls ...
openaire   +2 more sources

The Role of Decorin in Cancer

2022
Kornélia Baghy, Andrea Reszegi, Zsolt Horváth, Ilona Kovalszky   +3 more
openaire   +1 more source

Differentiated activities of decorin and biglycan in the progression of post-traumatic osteoarthritis

Osteoarthritis and Cartilage, 2021
Ling Qin, Dehan Kong, Lin Han
exaly  

Impact of Decorin on the Physical Function and Prognosis of Patients with Hepatocellular Carcinoma

Journal of Clinical Medicine, 2020
Takumi Kawaguchi, Sachiyo Yoshio, Yuzuru Sakamoto   +2 more
exaly  

The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis

FEBS Journal, 2007
Elke Schönherr, Horst Robenek, Uwe Hansen   +2 more
exaly